Square Wave Stripping Voltammetric Determination of Pantoprazole in Rabbit Plasma using Surfactant-based Pencil Graphite Electrode
Simple, inexpensive, accurate and sensitive square wave adsorptive stripping voltammetry method depends on oxidation of anti-ulcer drug pantoprazole sodium on pencil graphite electrode using sodium dodecyl sulphate as a surfactant at pH 6.0 was introduced. The current signal due to the oxidation pro...
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Veröffentlicht in: | Journal of analytical chemistry (New York, N.Y.) N.Y.), 2019-06, Vol.74 (6), p.609-616 |
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container_title | Journal of analytical chemistry (New York, N.Y.) |
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creator | Pakinaz Y. Khashaba Ali, Hassan Refat H. El-Wekil, Mohamed M. |
description | Simple, inexpensive, accurate and sensitive square wave adsorptive stripping voltammetry method depends on oxidation of anti-ulcer drug pantoprazole sodium on pencil graphite electrode using sodium dodecyl sulphate as a surfactant at pH 6.0 was introduced. The current signal due to the oxidation process as a function of the amount of the cited drug, pH of the medium, type of surfactant, frequency and adsorption time at the electrode surface was studied. The oxidation peak current varied linearly with the concentration over the range of 5 × 10
–9
–6 × 10
–6
M. The limit of detection was 2 nM. The validity of the proposed method for pharmacokinetic study in rabbit plasma was conducted. |
doi_str_mv | 10.1134/S106193481906008X |
format | Article |
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–9
–6 × 10
–6
M. The limit of detection was 2 nM. The validity of the proposed method for pharmacokinetic study in rabbit plasma was conducted.</description><identifier>ISSN: 1061-9348</identifier><identifier>EISSN: 1608-3199</identifier><identifier>DOI: 10.1134/S106193481906008X</identifier><language>eng</language><publisher>Moscow: Pleiades Publishing</publisher><subject>Adsorptivity ; Analytical Chemistry ; Chemistry ; Chemistry and Materials Science ; Electrodes ; Graphite ; Oxidation ; Pharmacology ; Signal processing ; Sodium dodecyl sulfate ; Square waves ; Stripping ; Surfactants ; Voltammetry</subject><ispartof>Journal of analytical chemistry (New York, N.Y.), 2019-06, Vol.74 (6), p.609-616</ispartof><rights>Pleiades Publishing, Ltd. 2019</rights><rights>Copyright Springer Nature B.V. 2019</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c316t-d461d13f727d05a44fa8c8b916f1c27b1d43ff8037314bc039c6ff0bd7eeb7c43</citedby><cites>FETCH-LOGICAL-c316t-d461d13f727d05a44fa8c8b916f1c27b1d43ff8037314bc039c6ff0bd7eeb7c43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1134/S106193481906008X$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1134/S106193481906008X$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids></links><search><creatorcontrib>Pakinaz Y. Khashaba</creatorcontrib><creatorcontrib>Ali, Hassan Refat H.</creatorcontrib><creatorcontrib>El-Wekil, Mohamed M.</creatorcontrib><title>Square Wave Stripping Voltammetric Determination of Pantoprazole in Rabbit Plasma using Surfactant-based Pencil Graphite Electrode</title><title>Journal of analytical chemistry (New York, N.Y.)</title><addtitle>J Anal Chem</addtitle><description>Simple, inexpensive, accurate and sensitive square wave adsorptive stripping voltammetry method depends on oxidation of anti-ulcer drug pantoprazole sodium on pencil graphite electrode using sodium dodecyl sulphate as a surfactant at pH 6.0 was introduced. The current signal due to the oxidation process as a function of the amount of the cited drug, pH of the medium, type of surfactant, frequency and adsorption time at the electrode surface was studied. The oxidation peak current varied linearly with the concentration over the range of 5 × 10
–9
–6 × 10
–6
M. The limit of detection was 2 nM. The validity of the proposed method for pharmacokinetic study in rabbit plasma was conducted.</description><subject>Adsorptivity</subject><subject>Analytical Chemistry</subject><subject>Chemistry</subject><subject>Chemistry and Materials Science</subject><subject>Electrodes</subject><subject>Graphite</subject><subject>Oxidation</subject><subject>Pharmacology</subject><subject>Signal processing</subject><subject>Sodium dodecyl sulfate</subject><subject>Square waves</subject><subject>Stripping</subject><subject>Surfactants</subject><subject>Voltammetry</subject><issn>1061-9348</issn><issn>1608-3199</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNp1kM1LxDAQxYsouH78Ad4CnquZJqbpUdZ1FQQX169bSdOJRtqmm6SCHv3L7bKCB_E0w7zfewMvSY6AngAwfroEKqBgXEJBBaXyeSuZgKAyZVAU2-M-yula3032QnijlBYSxCT5Wq4G5ZE8qXcky-ht39vuhTy6Jqq2xfGgyQVG9K3tVLSuI86Qheqi6736dA0S25E7VVU2kkWjQqvIENYJy8EbpeNIppUKWJMFdto2ZO5V_2ojklmDOnpX40GyY1QT8PBn7icPl7P76VV6czu_np7fpJqBiGnNBdTATJ7lNT1TnBsltawKEAZ0lldQc2aMpCxnwCtNWaGFMbSqc8Qq15ztJ8eb3N671YAhlm9u8N34sswyJkXGcyFHCjaU9i4Ej6bsvW2V_yiBluuqyz9Vj55s4wkj272g_03-3_QNt5eC3w</recordid><startdate>20190601</startdate><enddate>20190601</enddate><creator>Pakinaz Y. Khashaba</creator><creator>Ali, Hassan Refat H.</creator><creator>El-Wekil, Mohamed M.</creator><general>Pleiades Publishing</general><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20190601</creationdate><title>Square Wave Stripping Voltammetric Determination of Pantoprazole in Rabbit Plasma using Surfactant-based Pencil Graphite Electrode</title><author>Pakinaz Y. Khashaba ; Ali, Hassan Refat H. ; El-Wekil, Mohamed M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c316t-d461d13f727d05a44fa8c8b916f1c27b1d43ff8037314bc039c6ff0bd7eeb7c43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Adsorptivity</topic><topic>Analytical Chemistry</topic><topic>Chemistry</topic><topic>Chemistry and Materials Science</topic><topic>Electrodes</topic><topic>Graphite</topic><topic>Oxidation</topic><topic>Pharmacology</topic><topic>Signal processing</topic><topic>Sodium dodecyl sulfate</topic><topic>Square waves</topic><topic>Stripping</topic><topic>Surfactants</topic><topic>Voltammetry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pakinaz Y. Khashaba</creatorcontrib><creatorcontrib>Ali, Hassan Refat H.</creatorcontrib><creatorcontrib>El-Wekil, Mohamed M.</creatorcontrib><collection>CrossRef</collection><jtitle>Journal of analytical chemistry (New York, N.Y.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pakinaz Y. Khashaba</au><au>Ali, Hassan Refat H.</au><au>El-Wekil, Mohamed M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Square Wave Stripping Voltammetric Determination of Pantoprazole in Rabbit Plasma using Surfactant-based Pencil Graphite Electrode</atitle><jtitle>Journal of analytical chemistry (New York, N.Y.)</jtitle><stitle>J Anal Chem</stitle><date>2019-06-01</date><risdate>2019</risdate><volume>74</volume><issue>6</issue><spage>609</spage><epage>616</epage><pages>609-616</pages><issn>1061-9348</issn><eissn>1608-3199</eissn><abstract>Simple, inexpensive, accurate and sensitive square wave adsorptive stripping voltammetry method depends on oxidation of anti-ulcer drug pantoprazole sodium on pencil graphite electrode using sodium dodecyl sulphate as a surfactant at pH 6.0 was introduced. The current signal due to the oxidation process as a function of the amount of the cited drug, pH of the medium, type of surfactant, frequency and adsorption time at the electrode surface was studied. The oxidation peak current varied linearly with the concentration over the range of 5 × 10
–9
–6 × 10
–6
M. The limit of detection was 2 nM. The validity of the proposed method for pharmacokinetic study in rabbit plasma was conducted.</abstract><cop>Moscow</cop><pub>Pleiades Publishing</pub><doi>10.1134/S106193481906008X</doi><tpages>8</tpages></addata></record> |
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subjects | Adsorptivity Analytical Chemistry Chemistry Chemistry and Materials Science Electrodes Graphite Oxidation Pharmacology Signal processing Sodium dodecyl sulfate Square waves Stripping Surfactants Voltammetry |
title | Square Wave Stripping Voltammetric Determination of Pantoprazole in Rabbit Plasma using Surfactant-based Pencil Graphite Electrode |
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