$Personalized Dosimetry using 131I-anti-CD45-Apamistamab (Iomab-B) Prior to High-dose Myeloablative Radioimmunotherapy for Hematopoietic Stem Cell Transplant (HCT) in Active, Relapsed, or Refractory Acute Myelogenous Leukemia: Novel Re-induction and Targeted Conditioning Feasibility and Engraftment Results from the SIERRA Trial$

Personalized Dosimetry using 131I-anti-CD45-Apamistamab (Iomab-B) Prior to High-dose Myeloablative Radioimmunotherapy for Hematopoietic Stem Cell Transplant (HCT) in Active, Relapsed, or Refractory Acute Myelogenous Leukemia: Novel Re-induction and Targeted Conditioning Feasibility and Engraftment Results from the SIERRA Trial

Objectives: Innovative radiation therapy strategies are needed to effectively treat advanced acute myeloid leukemia (AML) in older patients, since toxicity may preclude high dose myeloablative radiation for allogeneic hematopoietic cell transplant (HCT). We show that re-induction and targeted myeloa...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of nuclear medicine (1978) 2019-05, Vol.60
Hauptverfasser:	Griffeth, Landis, Passalaqua, Susan, Wiseman, Gregory, Avril, Norbert, Yap, Wendell, Chen, Ming-Kai, Wagner, Robert, Natwa, Mona, Chasen, Beth, Lamonica, Dominick, Konerth, Sandy, Fisher, Darrell, Safavi, Farnoush, Berger, Mark, Reddy, Vijay, Pandit-Taskar, Neeta
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute myeloid leukemia Antibodies Attenuation CD45 antigen Complications Conditioning Dosimeters Dosimetry Feasibility studies Hematopoietic stem cells Image acquisition Immunotherapy Iodine Iodine 131 Iodine isotopes Iodine radioisotopes Kinetics Leukemia Liver Mathematical analysis Medical imaging Medical innovations Myeloid leukemia Patients Radiation dosage Radiation therapy Schedules Stem cell transplantation Stem cells Stroma Toxicity Transplants & implants
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!