Tuning the In Vivo Transport of Anticancer Drugs Using Renal‐Clearable Gold Nanoparticles

Precise control of in vivo transport of anticancer drugs in normal and cancerous tissues with engineered nanoparticles is key to the future success of cancer nanomedicines in clinics. This requires a fundamental understanding of how engineered nanoparticles impact the targeting‐clearance and permeat...

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Veröffentlicht in:	Angewandte Chemie International Edition 2019-06, Vol.58 (25), p.8479-8483
Hauptverfasser:	Peng, Chuanqi, Xu, Jing, Yu, Mengxiao, Ning, Xuhui, Huang, Yingyu, Du, Bujie, Hernandez, Elizabeth, Kapur, Payal, Hsieh, Jer‐Tsong, Zheng, Jie
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic drugs Antitumor agents Cancer Doxorubicin Drug delivery Drug delivery systems Drugs enhanced permeability and retention effect Gold gold nanoparticles Kidneys Nanoparticles Paradoxes Penetration Permeability renal clearance Retention Transport tumor targeting Tumors
Online-Zugang:	Volltext
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