Temporal immmunometabolic profiling of adipose tissue in HFD-induced obesity: manifestations of mast cells in fibrosis and senescence

Background/Objectives: Chronic low-grade inflammation/meta-inflammation in adipose tissue leads to obesity-associated metabolic complications. Despite growing understanding, the roles of immune cell subsets, their interrelationship, and chronological events leading to progression of obesity-associat...

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Veröffentlicht in:	International Journal of Obesity 2019-06, Vol.43 (6), p.1281-1294
Hauptverfasser:	Kumar, Durgesh, Pandya, Sanket Kumar, Varshney, Salil, Shankar, Kripa, Rajan, Sujith, Srivastava, Ankita, Gupta, Abhishek, Gupta, Sanchita, Vishwakarma, Achchhe Lal, Misra, Amit, Gaikwad, Anil N.
Format:	Artikel
Sprache:	eng
Schlagworte:	13/1 13/21 13/31 14/63 38/39 38/77 64/60 692/163/2743/2815 692/163/2743/393 82/1 82/16 82/80 Adipose tissue Adipose Tissue - immunology Adipose Tissue - metabolism Adipose Tissue - pathology Adipose tissues Aging Aging - pathology Animals Bisphosphonates Clodronic acid Collagen Depletion Diet, High-Fat Disease Models, Animal Epidemiology Fibrosis Fibrosis - pathology Flow cytometry Glucose Glucose tolerance Health Promotion and Disease Prevention High fat diet Histamine Histochemistry Homeostasis Immune system Inflammation Inflammation - metabolism Insulin Insulin Resistance Internal Medicine Intolerance Ketogenic diet Liposomes Lymphocytes T Macrophages Mast cells Mast Cells - pathology Medicine Medicine & Public Health Metabolic Diseases Metabolism Mice Mice, Inbred C57BL Obesity Obesity - immunology Obesity - metabolism Obesity - pathology p53 Protein Public Health Risk factors Senescence Sodium Stabilization Staining
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