Synthesis of Some Hybrid 7-Hydroxy Quinolinone Derivatives As Anti Breast Cancer Drugs

A new series of hybrid 2-Quinolinone derivatives were synthesized and structurally proved using spectral and elemental analyses data. All the prepared compounds were tested for their in vitro cytotoxic activity against MCF-7 cell line. Compounds 6 and 8 showed potent anticancer activity, which were...

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Veröffentlicht in:	Research on chemical intermediates 2019-07, Vol.45 (7), p.3895-3912
Hauptverfasser:	Moustafa, Amal Mahmoud Youssef, Bakare, Safyah B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticancer properties Apoptosis Breast cancer Catalysis Cell cycle Chemistry Chemistry and Materials Science Derivatives Doxorubicin Inorganic Chemistry Physical Chemistry Synthesis
Online-Zugang:	Volltext
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