Occurrence and distribution of pharmaceuticals in raw, finished, and drinking water from seven large river basins in China
The occurrence of pharmaceuticals in the drinking water is a growing concern in China. In this study, we determined the concentration and distribution of 59 selected pharmaceuticals in raw, finished, and tap water samples from 79 drinking water treatment plants (DWTPs) in 15 cities, encompassing sev...
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Veröffentlicht in: | Journal of water and health 2019-06, Vol.17 (3), p.477-489 |
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description | The occurrence of pharmaceuticals in the drinking water is a growing concern in China. In this study, we determined the concentration and distribution of 59 selected pharmaceuticals in raw, finished, and tap water samples from 79 drinking water treatment plants (DWTPs) in 15 cities, encompassing seven large river basins in China, using solid-phase extraction pretreatment and ultra-high-performance liquid chromatography-tandem mass spectrometry analysis. Forty-seven pharmaceuticals were detected in raw water samples, with detection rates of 1.27-96.20% and average concentrations of 0.09-128.87 ng/L. Forty-three pharmaceuticals were detected in finished water samples, with detection rates of 1.27-96.20% and average concentrations of 0.07-59.17 ng/L. Forty-two pharmaceuticals were detected in tap water samples, with detection rates of 1.27-94.94% and average concentrations of 0.07-58.43 ng/L. Purification methods implemented by DWTPs are capable of removing some pharmaceuticals from water treatment systems; however, low concentrations of pharmaceuticals were detected in drinking water, raising concerns about the possible human health implications of long-term exposure to low-dose pharmaceuticals. The detection and quantification of pharmaceuticals in municipal water samples presented in this study represent the most extensive analysis of commonly used pharmaceuticals and personal care products located in Chinese river basins. |
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In this study, we determined the concentration and distribution of 59 selected pharmaceuticals in raw, finished, and tap water samples from 79 drinking water treatment plants (DWTPs) in 15 cities, encompassing seven large river basins in China, using solid-phase extraction pretreatment and ultra-high-performance liquid chromatography-tandem mass spectrometry analysis. Forty-seven pharmaceuticals were detected in raw water samples, with detection rates of 1.27-96.20% and average concentrations of 0.09-128.87 ng/L. Forty-three pharmaceuticals were detected in finished water samples, with detection rates of 1.27-96.20% and average concentrations of 0.07-59.17 ng/L. Forty-two pharmaceuticals were detected in tap water samples, with detection rates of 1.27-94.94% and average concentrations of 0.07-58.43 ng/L. Purification methods implemented by DWTPs are capable of removing some pharmaceuticals from water treatment systems; however, low concentrations of pharmaceuticals were detected in drinking water, raising concerns about the possible human health implications of long-term exposure to low-dose pharmaceuticals. The detection and quantification of pharmaceuticals in municipal water samples presented in this study represent the most extensive analysis of commonly used pharmaceuticals and personal care products located in Chinese river basins.</description><identifier>ISSN: 1477-8920</identifier><identifier>EISSN: 1996-7829</identifier><identifier>DOI: 10.2166/wh.2019.250</identifier><identifier>PMID: 31095522</identifier><language>eng</language><publisher>England: IWA Publishing</publisher><subject>Acids ; Antibiotics ; Basins ; China ; Cities ; Consumer products ; Cosmetics industry ; Detection ; Distribution ; Drinking water ; Drinking Water - chemistry ; Drugs ; Effluents ; Environmental Monitoring ; Environmental protection ; Groundwater ; High performance liquid chromatography ; HPLC ; Humans ; Liquid chromatography ; Low concentrations ; Mass spectrometry ; Mass spectroscopy ; Municipal water ; Personal grooming ; Pharmaceutical Preparations - analysis ; Pharmaceuticals ; Pretreatment ; Purification ; Raw water ; River basins ; Rivers ; Rivers - chemistry ; Scientific imaging ; Solid phases ; Surface water ; Water analysis ; Water Pollutants, Chemical - analysis ; Water purification ; Water sampling ; Water treatment ; Water treatment plants ; Watershed management</subject><ispartof>Journal of water and health, 2019-06, Vol.17 (3), p.477-489</ispartof><rights>Copyright IWA Publishing Jun 2019</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c396t-efaf57ee155973ac565cf4d230358a3fa7fdfa72b0f941a7390b428f0d9ce0c83</citedby><cites>FETCH-LOGICAL-c396t-efaf57ee155973ac565cf4d230358a3fa7fdfa72b0f941a7390b428f0d9ce0c83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31095522$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lv, Jia</creatorcontrib><creatorcontrib>Zhang, Lan</creatorcontrib><creatorcontrib>Chen, Yongyan</creatorcontrib><creatorcontrib>Ye, Bixiong</creatorcontrib><creatorcontrib>Han, Jiayi</creatorcontrib><creatorcontrib>Jin, Ning</creatorcontrib><title>Occurrence and distribution of pharmaceuticals in raw, finished, and drinking water from seven large river basins in China</title><title>Journal of water and health</title><addtitle>J Water Health</addtitle><description>The occurrence of pharmaceuticals in the drinking water is a growing concern in China. In this study, we determined the concentration and distribution of 59 selected pharmaceuticals in raw, finished, and tap water samples from 79 drinking water treatment plants (DWTPs) in 15 cities, encompassing seven large river basins in China, using solid-phase extraction pretreatment and ultra-high-performance liquid chromatography-tandem mass spectrometry analysis. Forty-seven pharmaceuticals were detected in raw water samples, with detection rates of 1.27-96.20% and average concentrations of 0.09-128.87 ng/L. Forty-three pharmaceuticals were detected in finished water samples, with detection rates of 1.27-96.20% and average concentrations of 0.07-59.17 ng/L. Forty-two pharmaceuticals were detected in tap water samples, with detection rates of 1.27-94.94% and average concentrations of 0.07-58.43 ng/L. Purification methods implemented by DWTPs are capable of removing some pharmaceuticals from water treatment systems; however, low concentrations of pharmaceuticals were detected in drinking water, raising concerns about the possible human health implications of long-term exposure to low-dose pharmaceuticals. The detection and quantification of pharmaceuticals in municipal water samples presented in this study represent the most extensive analysis of commonly used pharmaceuticals and personal care products located in Chinese river basins.</description><subject>Acids</subject><subject>Antibiotics</subject><subject>Basins</subject><subject>China</subject><subject>Cities</subject><subject>Consumer products</subject><subject>Cosmetics industry</subject><subject>Detection</subject><subject>Distribution</subject><subject>Drinking water</subject><subject>Drinking Water - chemistry</subject><subject>Drugs</subject><subject>Effluents</subject><subject>Environmental Monitoring</subject><subject>Environmental protection</subject><subject>Groundwater</subject><subject>High performance liquid chromatography</subject><subject>HPLC</subject><subject>Humans</subject><subject>Liquid chromatography</subject><subject>Low concentrations</subject><subject>Mass spectrometry</subject><subject>Mass spectroscopy</subject><subject>Municipal water</subject><subject>Personal grooming</subject><subject>Pharmaceutical Preparations - analysis</subject><subject>Pharmaceuticals</subject><subject>Pretreatment</subject><subject>Purification</subject><subject>Raw water</subject><subject>River basins</subject><subject>Rivers</subject><subject>Rivers - chemistry</subject><subject>Scientific imaging</subject><subject>Solid phases</subject><subject>Surface water</subject><subject>Water analysis</subject><subject>Water Pollutants, Chemical - analysis</subject><subject>Water purification</subject><subject>Water sampling</subject><subject>Water treatment</subject><subject>Water treatment plants</subject><subject>Watershed management</subject><issn>1477-8920</issn><issn>1996-7829</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNo9kD1PwzAQhi0EoqUwsSNLjDTFH3ESj6jiS6rUBWbLcezGpXGKnTSCX49LC8vd6fTec9IDwDVGM4Kz7H6oZwRhPiMMnYAx5jxL8oLw0zineZ4UnKARuAhhjRDJCCPnYEQx4owRMgbfS6V677VTGkpXwcqGztuy72zrYGvgtpa-kUrHhZKbAK2DXg5TaKyzodbV9HDlrfuwbgUH2WkPjW8bGPROO7iRfqWht7u4LmWw7hcxr62Tl-DMRKS-OvYJeH96fJu_JIvl8-v8YZEoyrMu0UYalmuNGeM5lYplTJm0IhRRVkhqZG6qWEiJDE-xzClHZUoKgyquNFIFnYDbA3fr289eh06s2967-FIQQlPCGcYspu4OKeXbELw2YuttI_2XwEjsPYuhFnvPInqO6Zsjsy8bXf1n_8TSHy2Iegw</recordid><startdate>20190601</startdate><enddate>20190601</enddate><creator>Lv, Jia</creator><creator>Zhang, Lan</creator><creator>Chen, Yongyan</creator><creator>Ye, Bixiong</creator><creator>Han, Jiayi</creator><creator>Jin, Ning</creator><general>IWA Publishing</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QH</scope><scope>7UA</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BKSAR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>F1W</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H97</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>L.G</scope><scope>M0S</scope><scope>M1P</scope><scope>PATMY</scope><scope>PCBAR</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PYCSY</scope></search><sort><creationdate>20190601</creationdate><title>Occurrence and distribution of pharmaceuticals in raw, finished, and drinking water from seven large river basins in China</title><author>Lv, Jia ; Zhang, Lan ; Chen, Yongyan ; Ye, Bixiong ; Han, Jiayi ; Jin, Ning</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c396t-efaf57ee155973ac565cf4d230358a3fa7fdfa72b0f941a7390b428f0d9ce0c83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Acids</topic><topic>Antibiotics</topic><topic>Basins</topic><topic>China</topic><topic>Cities</topic><topic>Consumer products</topic><topic>Cosmetics industry</topic><topic>Detection</topic><topic>Distribution</topic><topic>Drinking water</topic><topic>Drinking Water - 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In this study, we determined the concentration and distribution of 59 selected pharmaceuticals in raw, finished, and tap water samples from 79 drinking water treatment plants (DWTPs) in 15 cities, encompassing seven large river basins in China, using solid-phase extraction pretreatment and ultra-high-performance liquid chromatography-tandem mass spectrometry analysis. Forty-seven pharmaceuticals were detected in raw water samples, with detection rates of 1.27-96.20% and average concentrations of 0.09-128.87 ng/L. Forty-three pharmaceuticals were detected in finished water samples, with detection rates of 1.27-96.20% and average concentrations of 0.07-59.17 ng/L. Forty-two pharmaceuticals were detected in tap water samples, with detection rates of 1.27-94.94% and average concentrations of 0.07-58.43 ng/L. Purification methods implemented by DWTPs are capable of removing some pharmaceuticals from water treatment systems; however, low concentrations of pharmaceuticals were detected in drinking water, raising concerns about the possible human health implications of long-term exposure to low-dose pharmaceuticals. The detection and quantification of pharmaceuticals in municipal water samples presented in this study represent the most extensive analysis of commonly used pharmaceuticals and personal care products located in Chinese river basins.</abstract><cop>England</cop><pub>IWA Publishing</pub><pmid>31095522</pmid><doi>10.2166/wh.2019.250</doi><tpages>13</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Acids Antibiotics Basins China Cities Consumer products Cosmetics industry Detection Distribution Drinking water Drinking Water - chemistry Drugs Effluents Environmental Monitoring Environmental protection Groundwater High performance liquid chromatography HPLC Humans Liquid chromatography Low concentrations Mass spectrometry Mass spectroscopy Municipal water Personal grooming Pharmaceutical Preparations - analysis Pharmaceuticals Pretreatment Purification Raw water River basins Rivers Rivers - chemistry Scientific imaging Solid phases Surface water Water analysis Water Pollutants, Chemical - analysis Water purification Water sampling Water treatment Water treatment plants Watershed management |
title | Occurrence and distribution of pharmaceuticals in raw, finished, and drinking water from seven large river basins in China |
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