The fungicide procymidone alters sexual differentiation in the male rat by acting as an androgen-receptor antagonist in vivo and in vitro

Procymidone is a dicarboximide fungicide structurally related to the well-characterized fungicide vinclozolin. Vinclozolin metabolites bind to mammalian androgen receptors (AR) and act as AR antagonists, inhibiting androgen-dependent gene expression in vivo and in vitro by inhibiting AR-binding to D...

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Veröffentlicht in:	Toxicology and industrial health 1999-01, Vol.15 (1), p.80-93
Hauptverfasser:	Ostby, J., Kelce, W.R., Lambright, C., Wolf, C.J., Mann, P., Gray, L.E.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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