Identification of a targeting‐delivery peptide based on rhCNB

Calcineurin B subunit (CNB) is the regulatory subunit of calcineurin (CN), and its classical function is to regulate the activity of CN. Research in our laboratory has revealed that the recombinant human CNB (rhCNB) is a good antitumor candidate and can be internalized by tumor cells via TLR4 recept...

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Veröffentlicht in:	Journal of peptide science 2019-06, Vol.25 (6), p.e3159-n/a
Hauptverfasser:	Yang, Jinju, Gao, Yadan, Zhu, Ziwei, Qin, Nannan, Wei, Qun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal tissues Calcineurin cellular uptake Drug delivery Drug delivery systems Enzyme-linked immunosorbent assay Immunoprecipitation Internalization Mice Peptides Recombinant DNA targeting delivery TLR4 TLR4 protein Toll-like receptors truncated rhCNBs Tumor cells Tumors
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