Blockage of Ca2+-permeable AMPA receptors suppresses migration and induces apoptosis in human glioblastoma cells

Glioblastoma multiforme is the most undifferentiated type of brain tumor, and its prognosis is extremely poor. Glioblastoma cells exhibit highly migratory and invasive behavior, which makes surgical intervention unsuccessful. Here, we showed that glioblastoma cells express Ca 2+ -permeable α-amino-3...

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Veröffentlicht in:	Nature medicine 2002-09, Vol.8 (9), p.971-978
Hauptverfasser:	Ishiuchi, Shogo, Tsuzuki, Keisuke, Yoshida, Yukari, Yamada, Nobuaki, Hagimura, Norikazu, Okado, Haruo, Miwa, Akiko, Kurihara, Hideyuki, Nakazato, Yoichi, Tamura, Masaru, Sasaki, Tomio, Ozawa, Seiji
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Apoptosis Biomedical and Life Sciences Biomedicine Brain cancer Brain tumors Cancer Research Hybridization Infectious Diseases Medicine Metabolic Diseases Molecular Medicine Neurosciences Neurosurgery Permeability Prevention
Online-Zugang:	Volltext
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