Nicotinamide Phosphate Transferase (NAMPT) Increases in Plasma in Patients with Acute Coronary Syndromes, and Promotes Macrophages to M2 Polarization

Atherosclerosis is an inflammatory disease; monocytes and macrophages play an important role in the progression of this disease. However, the mechanisms are not fully understood yet. Nicotinamide phosphate transferase (NAMPT) is the rate limiting enzyme in the synthesis of NAD, but extracellular NAM...

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Veröffentlicht in:	International Heart Journal 2018/09/01, Vol.59(5), pp.1116-1122
Hauptverfasser:	Zhang, Chengxin, Zhu, Rui, Wang, Huiping, Tao, Qianshan, Lin, Xianhe, Ge, Shenglin, Zhai, Zhimin
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute coronary syndromes Arteriosclerosis Atherosclerosis Cell culture Inflammatory diseases Interleukin 1 receptor antagonist Interleukin 1 receptors Interleukin 10 Interleukin 13 Interleukin 4 Interleukin 6 Macrophage polarization Macrophages Monocytes NAD NADPH Nicotinamide Peripheral blood mononuclear cells Polarization Signal transduction SIRT1 protein
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