Glycometabolic Bioorthogonal Chemistry‐Guided Viral Transduction for Robust Human T Cell Engineering

Genetically engineered T cell therapy is emerging as a potent strategy for treating hematological and solid malignancies. Although lentivirus is the most common vector for T cell gene modification, its transduction efficacy remains unsatisfied especially during the manufacturing process. Herein, gly...

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Veröffentlicht in:	Advanced functional materials 2019-05, Vol.29 (22), p.n/a
Hauptverfasser:	Pan, Hong, Li, Ping, Li, Guifei, Li, Wenjun, Hu, Bian, He, Huamei, Chen, Ze, Wang, Fangfang, Liu, Lanlan, Gong, Yifeng, Han, Yutong, Luo, Yingmei, Zheng, Mingbin, Ma, Yifan, Cai, Lintao, Jin, Yan
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens azide–glucose Binding Genetic engineering Genetic modification Glucose glycometabolic bioorthogonal chemistry Lymphocytes Materials science Organic chemistry T cell engineering viral transduction Viruses
Online-Zugang:	Volltext
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