Role of the Decrement in Intraislet Insulin for the Glucagon Response to Hypoglycemia in Humans

OBJECTIVE:--Animal and in vitro studies indicate that a decrease in {szligbeta}-cell insulin secretion, and thus a decrease in tonic [alpha]-cell inhibition by intraislet insulin, may be an important factor for the increase in glucagon secretion during hypoglycemia. However, in humans this role of d...

Ausführliche Beschreibung