Dendritic polymers composed of glycerol and succinic acid: Synthetic methodologies and medical applications
Research on dendrimers continues to expand as further advances in synthetic methodology and characterization techniques translate to additional applications. Recently, dendritic polymers composed of the natural metabolites glycerol and succinic acid were synthesized, functionalized, and evaluated as...
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| Veröffentlicht in: | Pure and applied chemistry 2004-01, Vol.76 (7), p.1375-1385 |
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| container_end_page | 1385 |
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| container_issue | 7 |
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| container_title | Pure and applied chemistry |
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| creator | Luman, N. R. Kim, Terry Grinstaff, M. W. |
| description | Research on dendrimers continues to expand as further advances in synthetic methodology and characterization techniques translate to additional applications. Recently, dendritic polymers composed of the natural metabolites glycerol and succinic acid were synthesized, functionalized, and evaluated as new medical materials. The design and synthesis of poly(glycerol-succinic acid) dendritic polymers are discussed, including comparing and contrasting the convergent versus the divergent methodologies for preparing such macromolecules. Finally, a photocrosslinkable dendritic macromolecule was prepared and successfully used to close linear corneal lacerations as well as to secure LASIK flaps. |
| doi_str_mv | 10.1351/pac200476071375 |
| format | Article |
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Finally, a photocrosslinkable dendritic macromolecule was prepared and successfully used to close linear corneal lacerations as well as to secure LASIK flaps.</description><subject>Addition polymerization</subject><subject>Chemical synthesis</subject><subject>Dendrimers</subject><subject>Dendritic structure</subject><subject>Flaps</subject><subject>Glycerol</subject><subject>Macromolecules</subject><subject>Medical materials</subject><subject>Medical research</subject><subject>Metabolites</subject><subject>Polymers</subject><subject>Succinic acid</subject><issn>0033-4545</issn><issn>1365-3075</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><recordid>eNp1kEtLxDAUhYMoOI6u3RZc10mapGldKeMTBlyo65LHzUzGtqlJi_Tf23EEQXB1z-L7zoWD0DnBl4RysuikzjBmIseCUMEP0IzQnKcUC36IZhhTmjLO-DE6iXGLJ7Jk2Qy930JrguudTjpfjw2EmGjfdD6CSbxN1vWoIfg6ka1J4qC1aydUameukpex7TewUxvoN9742q8dxG-0AeO0nLSuq6fQO9_GU3RkZR3h7OfO0dv93evyMV09Pzwtb1apZpT0qVRUgCqLXJscmFGMZ0IqZkHpHIyFzBLMqLA5MwU30kilC0WtYcpkRFlB5-hi39sF_zFA7KutH0I7vayyLCvLEnNRTNRiT-ngYwxgqy64RoaxIrjaLVr9WXQyrvfGp6x7CAbWYRin8Fv_jylyURXfFV_4bYEu</recordid><startdate>20040101</startdate><enddate>20040101</enddate><creator>Luman, N. 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| fulltext | fulltext |
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| ispartof | Pure and applied chemistry, 2004-01, Vol.76 (7), p.1375-1385 |
| issn | 0033-4545 1365-3075 |
| language | eng |
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| source | EZB-FREE-00999 freely available EZB journals; Free Full-Text Journals in Chemistry |
| subjects | Addition polymerization Chemical synthesis Dendrimers Dendritic structure Flaps Glycerol Macromolecules Medical materials Medical research Metabolites Polymers Succinic acid |
| title | Dendritic polymers composed of glycerol and succinic acid: Synthetic methodologies and medical applications |
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