Effect of Geranylgeranyl Pyrophosphate Synthase on Hypoxia/Reoxygenation-Induced Injury in Heart-Derived H9c2 Cells

Recent studies have revealed that geranylgeranyl pyrophosphate synthase (GGPPS), a key enzyme involved in protein prenylation, plays a critical role in postnatal heart growth by regulating cardiomyocyte size. However, the role of GGPPS in myocardial ischemia/reperfusion (MIR) injury is still not cle...

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Veröffentlicht in:	International Heart Journal 2018/07/31, Vol.59(4), pp.821-828
Hauptverfasser:	Dai, Dongpu, Yang, Jian, Zhao, Chenze, Wu, Huandong, Ding, Jie, Sun, Xiaotong, Hu, Shenjiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Cardiomyocytes Cell injury Cell viability Hypoxia Ischemia Myocardial ischemia NADPH oxidases Rac1 Rac1 protein Reactive oxygen species Reperfusion
Online-Zugang:	Volltext
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