Methods for the Preparation and Manufacture of Polymeric Nanoparticles
This review summarizes the different methods of preparation of polymer nanoparticles including nanospheres and nanocapsules. The first part summarizes the basic principle of each method of nanoparticle preparation. It presents the most recent innovations and progresses obtained over the last decade...
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| Veröffentlicht in: | Pharmaceutical research 2009-05, Vol.26 (5), p.1025-1058 |
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| creator | Vauthier, Christine Bouchemal, Kawthar |
| description | This review summarizes the different methods of preparation of polymer nanoparticles including nanospheres and nanocapsules. The first part summarizes the basic principle of each method of nanoparticle preparation. It presents the most recent innovations and progresses obtained over the last decade and which were not included in previous reviews on the subject. Strategies for the obtaining of nanoparticles with controlled
in vivo
fate are described in the second part of the review. A paragraph summarizing scaling up of nanoparticle production and presenting corresponding pilot set-up is considered in the third part of the review. Treatments of nanoparticles, applied after the synthesis, are described in the next part including purification, sterilization, lyophilization and concentration. Finally, methods to obtain labelled nanoparticles for
in vitro
and
in vivo
investigations are described in the last part of this review. |
| doi_str_mv | 10.1007/s11095-008-9800-3 |
| format | Article |
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in vivo
fate are described in the second part of the review. A paragraph summarizing scaling up of nanoparticle production and presenting corresponding pilot set-up is considered in the third part of the review. Treatments of nanoparticles, applied after the synthesis, are described in the next part including purification, sterilization, lyophilization and concentration. Finally, methods to obtain labelled nanoparticles for
in vitro
and
in vivo
investigations are described in the last part of this review.</description><identifier>ISSN: 0724-8741</identifier><identifier>EISSN: 1573-904X</identifier><identifier>DOI: 10.1007/s11095-008-9800-3</identifier><identifier>PMID: 19107579</identifier><identifier>CODEN: PHREEB</identifier><language>eng</language><publisher>Boston: Springer US</publisher><subject>Animals ; Biochemistry ; Biological and medical sciences ; Biomedical and Life Sciences ; Biomedical Engineering and Bioengineering ; Biomedical research ; Biomedicine ; Drug Carriers - administration & dosage ; Drug Carriers - chemistry ; Drug Carriers - pharmacokinetics ; Expert Review ; Freeze Drying ; General pharmacology ; Humans ; Materials science ; Medical Law ; Medical sciences ; Nanoparticles ; Nanoparticles - administration & dosage ; Nanoparticles - chemistry ; Nanoparticles - therapeutic use ; Nanotechnology - instrumentation ; Nanotechnology - methods ; Pharmaceutical technology. Pharmaceutical industry ; Pharmacology ; Pharmacology. Drug treatments ; Pharmacology/Toxicology ; Pharmacy ; Polymers ; Polymers - chemistry ; Process engineering ; Sterilization</subject><ispartof>Pharmaceutical research, 2009-05, Vol.26 (5), p.1025-1058</ispartof><rights>Springer Science+Business Media, LLC 2008</rights><rights>2009 INIST-CNRS</rights><rights>Springer Science+Business Media, LLC 2009</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c465t-6ff6a23bc3391721b6965bc70b3ef79bd313a385e43eaeb765457d9b6e5f3e193</citedby><cites>FETCH-LOGICAL-c465t-6ff6a23bc3391721b6965bc70b3ef79bd313a385e43eaeb765457d9b6e5f3e193</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11095-008-9800-3$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11095-008-9800-3$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=21402650$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19107579$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Vauthier, Christine</creatorcontrib><creatorcontrib>Bouchemal, Kawthar</creatorcontrib><title>Methods for the Preparation and Manufacture of Polymeric Nanoparticles</title><title>Pharmaceutical research</title><addtitle>Pharm Res</addtitle><addtitle>Pharm Res</addtitle><description>This review summarizes the different methods of preparation of polymer nanoparticles including nanospheres and nanocapsules. The first part summarizes the basic principle of each method of nanoparticle preparation. It presents the most recent innovations and progresses obtained over the last decade and which were not included in previous reviews on the subject. Strategies for the obtaining of nanoparticles with controlled
in vivo
fate are described in the second part of the review. A paragraph summarizing scaling up of nanoparticle production and presenting corresponding pilot set-up is considered in the third part of the review. Treatments of nanoparticles, applied after the synthesis, are described in the next part including purification, sterilization, lyophilization and concentration. Finally, methods to obtain labelled nanoparticles for
in vitro
and
in vivo
investigations are described in the last part of this review.</description><subject>Animals</subject><subject>Biochemistry</subject><subject>Biological and medical sciences</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedical Engineering and Bioengineering</subject><subject>Biomedical research</subject><subject>Biomedicine</subject><subject>Drug Carriers - administration & dosage</subject><subject>Drug Carriers - chemistry</subject><subject>Drug Carriers - pharmacokinetics</subject><subject>Expert Review</subject><subject>Freeze Drying</subject><subject>General pharmacology</subject><subject>Humans</subject><subject>Materials science</subject><subject>Medical Law</subject><subject>Medical sciences</subject><subject>Nanoparticles</subject><subject>Nanoparticles - administration & dosage</subject><subject>Nanoparticles - chemistry</subject><subject>Nanoparticles - therapeutic use</subject><subject>Nanotechnology - instrumentation</subject><subject>Nanotechnology - methods</subject><subject>Pharmaceutical technology. Pharmaceutical industry</subject><subject>Pharmacology</subject><subject>Pharmacology. Drug treatments</subject><subject>Pharmacology/Toxicology</subject><subject>Pharmacy</subject><subject>Polymers</subject><subject>Polymers - chemistry</subject><subject>Process engineering</subject><subject>Sterilization</subject><issn>0724-8741</issn><issn>1573-904X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kLtOwzAUhi0EoqXwACwoQmIM-BLH9YgqCkgtdACJzXKcY5oqjYudDH17XCWiE9MZzvefy4fQNcH3BGPxEAjBkqcYT1M5xThlJ2hMuGCpxNnXKRpjQbN0KjIyQhchbHAEiczO0YhIggUXcozmS2jXrgyJdT5p15CsPOy0123lmkQ3ZbLUTWe1aTsPibPJytX7LfjKJG-6cZFsK1NDuERnVtcBroY6QZ_zp4_ZS7p4f36dPS5Sk-W8TXNrc01ZYRiTRFBS5DLnhRG4YGCFLEpGmGZTDhkDDYXIecZFKYscuGVAJJug237uzrufDkKrNq7zTVypKKXxXc5ZhEgPGe9C8GDVzldb7feKYHUQp3pxKvpQB3HqkLkZBnfFFspjYjAVgbsB0MHo2nrdmCr8cZRkmOYcR472XIit5hv88cL_t_8CNxmE9A</recordid><startdate>20090501</startdate><enddate>20090501</enddate><creator>Vauthier, Christine</creator><creator>Bouchemal, Kawthar</creator><general>Springer US</general><general>Springer</general><general>Springer Nature B.V</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope></search><sort><creationdate>20090501</creationdate><title>Methods for the Preparation and Manufacture of Polymeric Nanoparticles</title><author>Vauthier, Christine ; Bouchemal, Kawthar</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c465t-6ff6a23bc3391721b6965bc70b3ef79bd313a385e43eaeb765457d9b6e5f3e193</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Animals</topic><topic>Biochemistry</topic><topic>Biological and medical sciences</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedical Engineering and Bioengineering</topic><topic>Biomedical research</topic><topic>Biomedicine</topic><topic>Drug Carriers - administration & dosage</topic><topic>Drug Carriers - chemistry</topic><topic>Drug Carriers - pharmacokinetics</topic><topic>Expert Review</topic><topic>Freeze Drying</topic><topic>General pharmacology</topic><topic>Humans</topic><topic>Materials science</topic><topic>Medical Law</topic><topic>Medical sciences</topic><topic>Nanoparticles</topic><topic>Nanoparticles - administration & dosage</topic><topic>Nanoparticles - chemistry</topic><topic>Nanoparticles - therapeutic use</topic><topic>Nanotechnology - instrumentation</topic><topic>Nanotechnology - methods</topic><topic>Pharmaceutical technology. Pharmaceutical industry</topic><topic>Pharmacology</topic><topic>Pharmacology. Drug treatments</topic><topic>Pharmacology/Toxicology</topic><topic>Pharmacy</topic><topic>Polymers</topic><topic>Polymers - chemistry</topic><topic>Process engineering</topic><topic>Sterilization</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vauthier, Christine</creatorcontrib><creatorcontrib>Bouchemal, Kawthar</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><jtitle>Pharmaceutical research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vauthier, Christine</au><au>Bouchemal, Kawthar</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Methods for the Preparation and Manufacture of Polymeric Nanoparticles</atitle><jtitle>Pharmaceutical research</jtitle><stitle>Pharm Res</stitle><addtitle>Pharm Res</addtitle><date>2009-05-01</date><risdate>2009</risdate><volume>26</volume><issue>5</issue><spage>1025</spage><epage>1058</epage><pages>1025-1058</pages><issn>0724-8741</issn><eissn>1573-904X</eissn><coden>PHREEB</coden><abstract>This review summarizes the different methods of preparation of polymer nanoparticles including nanospheres and nanocapsules. The first part summarizes the basic principle of each method of nanoparticle preparation. It presents the most recent innovations and progresses obtained over the last decade and which were not included in previous reviews on the subject. Strategies for the obtaining of nanoparticles with controlled
in vivo
fate are described in the second part of the review. A paragraph summarizing scaling up of nanoparticle production and presenting corresponding pilot set-up is considered in the third part of the review. Treatments of nanoparticles, applied after the synthesis, are described in the next part including purification, sterilization, lyophilization and concentration. Finally, methods to obtain labelled nanoparticles for
in vitro
and
in vivo
investigations are described in the last part of this review.</abstract><cop>Boston</cop><pub>Springer US</pub><pmid>19107579</pmid><doi>10.1007/s11095-008-9800-3</doi><tpages>34</tpages></addata></record> |
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| source | MEDLINE; SpringerNature Journals |
| subjects | Animals Biochemistry Biological and medical sciences Biomedical and Life Sciences Biomedical Engineering and Bioengineering Biomedical research Biomedicine Drug Carriers - administration & dosage Drug Carriers - chemistry Drug Carriers - pharmacokinetics Expert Review Freeze Drying General pharmacology Humans Materials science Medical Law Medical sciences Nanoparticles Nanoparticles - administration & dosage Nanoparticles - chemistry Nanoparticles - therapeutic use Nanotechnology - instrumentation Nanotechnology - methods Pharmaceutical technology. Pharmaceutical industry Pharmacology Pharmacology. Drug treatments Pharmacology/Toxicology Pharmacy Polymers Polymers - chemistry Process engineering Sterilization |
| title | Methods for the Preparation and Manufacture of Polymeric Nanoparticles |
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