Clinical Pharmacokinetics and Pharmacodynamics of Etravirine

Etravirine is a next-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) developed for the treatment of HIV-1 infection. It has a high genetic barrier to the emergence of viral resistance, and maintains its antiviral activity in the presence of common NNRTI mutations. The pharmacokinet...

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Veröffentlicht in:	Clinical pharmacokinetics 2009-01, Vol.48 (9), p.561-574
Hauptverfasser:	Schöller-Gyüre, Monika, Kakuda, Thomas N., Raoof, Araz, De Smedt, Goedele, Hoetelmans, Richard M. W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-HIV Agents - metabolism Anti-HIV Agents - pharmacokinetics Anti-HIV Agents - therapeutic use Biological and medical sciences Dosage and administration Drug Interactions Etravirine General pharmacology HIV Infections - drug therapy HIV Infections - metabolism Humans Internal Medicine Medical sciences Medicine Medicine & Public Health Pharmacokinetics Pharmacokinetics. Pharmacogenetics. Drug-receptor interactions Pharmacology Pharmacology. Drug treatments Pharmacology/Toxicology Pharmacotherapy Pyridazines - metabolism Pyridazines - pharmacokinetics Pyridazines - therapeutic use Reverse Transcriptase Inhibitors - metabolism Reverse Transcriptase Inhibitors - pharmacokinetics Reverse Transcriptase Inhibitors - therapeutic use Review Article
Online-Zugang:	Volltext
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