Microsensor-aided measurements of cellular signalling and metabolism on tumor cells : The cell monitoring system (CMS®)

Microsensors provide instruments particularly suited for the rapid, noninvasive and on-line analysis of cell and tissue cultures. The microsensor system presented in this paper is a modular arrangement of various planar and nonplanar sensor elements for the measurement of physiological parameters of...

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Veröffentlicht in:Tumor biology 1998, Vol.19 (5), p.374-383
Hauptverfasser: WOLF, B, BRISCHWEIN, M, BAUMAN, W, EHRET, R, HENNING, T, LEHMAN, M, SCHWINDE, A
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container_end_page 383
container_issue 5
container_start_page 374
container_title Tumor biology
container_volume 19
creator WOLF, B
BRISCHWEIN, M
BAUMAN, W
EHRET, R
HENNING, T
LEHMAN, M
SCHWINDE, A
description Microsensors provide instruments particularly suited for the rapid, noninvasive and on-line analysis of cell and tissue cultures. The microsensor system presented in this paper is a modular arrangement of various planar and nonplanar sensor elements for the measurement of physiological parameters of cell cultures. An optic access to the cultures (e.g. for light microscopy and spectrophotometric techniques) is also provided for a parallel and comparative data acquisition. The system was originally designed for biomedical research in chemotherapy (predicative chemotherapy assays) and pharmacology but it turned out to be also an effective tool for toxicological and environmental research.
doi_str_mv 10.1159/000030030
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ispartof Tumor biology, 1998, Vol.19 (5), p.374-383
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language eng
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source MEDLINE; Karger Journals
subjects Biological and medical sciences
Biosensing Techniques
Cell Adhesion
Cells, Cultured
Colonic Neoplasms - metabolism
Culture Media
Electric Impedance
Humans
Hydrogen-Ion Concentration
Investigative techniques, diagnostic techniques (general aspects)
Medical sciences
Miscellaneous. Technology
Oxygen - analysis
Oxygen - metabolism
Partial Pressure
Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques
Signal Transduction
title Microsensor-aided measurements of cellular signalling and metabolism on tumor cells : The cell monitoring system (CMS®)
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