CYCLOOXYGENASE-2: A Therapeutic Target

Cyclooxygenase (COX), also known as prostaglandin endoperoxide synthase, is the key enzyme required for the conversion of arachidonic acid to prostaglandins. Two COX isoforms have been identified, COX-1 and COX-2. In many situations, the COX-1 enzyme is produced constitutively (e.g., in gastric muco...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Annual review of medicine 2002-01, Vol.53 (1), p.35-57
Hauptverfasser:	Turini, Marco E, DuBois, Raymond N
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-inflammatory agents Anti-Inflammatory Agents, Non-Steroidal - adverse effects Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Arthritis Biology Cartilage Clinical Trials as Topic cyclooxygenase Cyclooxygenase 1 Cyclooxygenase 2 Cyclooxygenase 2 Inhibitors Cyclooxygenase Inhibitors - adverse effects Cyclooxygenase Inhibitors - therapeutic use Cytokines disease Enzymes Humans Inflammation Inflammation - drug therapy Inflammation - enzymology Isoenzymes - antagonists & inhibitors Membrane Proteins Neoplasms - drug therapy Neoplasms - enzymology Nitric oxide Nonsteroidal anti-inflammatory drugs Osteoarthritis Physiology Prostaglandin-Endoperoxide Synthases prostaglandins
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!