Drosophila Ric-8 regulates G[alpha]i cortical localization to promote G[alpha]i-dependent planar orientation of the mitotic spindle during asymmetric cell division

Localization and activation of heterotrimeric G proteins have a crucial role during asymmetric cell division. The asymmetric division of the Drosophila sensory precursor cell (pl) is polarized along the antero-posterior axis by Frizzled signalling and, during this division, activation of Galphai dep...

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Veröffentlicht in:Nature cell biology 2005-11, Vol.7 (11), p.1083
Hauptverfasser: David, Nicolas B, Martin, Charlotte A, Segalen, Marion, Rosenfeld, François, Schweisguth, François, Bellaïche, Yohanns
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Sprache:eng
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