AP-4 binds basolateral signals and participates in basolateral sorting in epithelial MDCK cells

Adaptors are heterotetrameric complexes that mediate the incorporation of cargo into transport vesicles by interacting with sorting signals present in the cytosolic domain of transmembrane proteins. Four adaptors, AP-1 (β1, γ, μ1A or μ1B, σ1), AP-2 (β2, α, μ2, σ2), AP-3 (β3, δ, μ3, σ3) or AP-4 (β4,...

Ausführliche Beschreibung