The sulfite molecule enhances homocysteine toxicity in SH-SY5Y cells

Homocysteine (hcy) is an amino acid that contains sulfur species. In healthy individuals, plasma hcy levels are low. The aim of this study was to investigate the potential neurotoxic effects of hcy and sulfite (sft) molecules alone and in their combination, and also to identify the relationship of t...

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Veröffentlicht in:	Molecular biology reports 2019-08, Vol.46 (4), p.4017-4025
Hauptverfasser:	Gundogdu, Gulsah, Dodurga, Yavuz, Kucukatay, Vural
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Amino Acids, Sulfur - metabolism Animal Anatomy Animal Biochemistry Antioxidants Antioxidants - metabolism Biomedical and Life Sciences Cell Line, Tumor Comet Assay Cytotoxicity DNA damage DNA Damage - drug effects Genotoxicity Histology Homocysteine Homocysteine - metabolism Homocysteine - toxicity Humans Life Sciences Lipid Peroxidation - drug effects Morphology Neurodegenerative diseases Neurodegenerative Diseases - metabolism Neurotoxicity Original Article Oxidative stress Oxidative Stress - drug effects Sulfite Sulfite Oxidase - metabolism Sulfites - metabolism Sulfites - toxicity Sulfur
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