Synthesis, Characterization, and Evaluation of Antibacterial and Antioxidant Activities of Novel Benzoxazinones and Benzoxathiinones
In this work, the new benzoxazinones and benzoxathiinones were synthesized from reaction of alkyl X‐phenylpropiolates and aminophenol (or 2‐mercaptophenol) in the presence of triphenylphosphine. Their antibacterial activities were studied against Gram‐positive bacteria and Gram‐negative bacteria usi...
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| Veröffentlicht in: | Journal of heterocyclic chemistry 2019-05, Vol.56 (5), p.1505-1513 |
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| container_title | Journal of heterocyclic chemistry |
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| creator | Gholami, Hamid Reza Asghari, Sakineh Mohseni, Mojtaba |
| description | In this work, the new benzoxazinones and benzoxathiinones were synthesized from reaction of alkyl X‐phenylpropiolates and aminophenol (or 2‐mercaptophenol) in the presence of triphenylphosphine. Their antibacterial activities were studied against Gram‐positive bacteria and Gram‐negative bacteria using the disc diffusion method. The obtained results showed that these compounds are more effective against Gram‐positive bacteria than against Gram‐negative bacteria. Also, evaluation of antioxidant activity of the obtained products showed that they have high to excellent antioxidant activity (79.2–93.6%). |
| doi_str_mv | 10.1002/jhet.3523 |
| format | Article |
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Their antibacterial activities were studied against Gram‐positive bacteria and Gram‐negative bacteria using the disc diffusion method. The obtained results showed that these compounds are more effective against Gram‐positive bacteria than against Gram‐negative bacteria. 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| ispartof | Journal of heterocyclic chemistry, 2019-05, Vol.56 (5), p.1505-1513 |
| issn | 0022-152X 1943-5193 |
| language | eng |
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| source | Wiley Online Library Journals Frontfile Complete |
| subjects | Aminophenol Antioxidants Bacteria Chemical synthesis Evaluation |
| title | Synthesis, Characterization, and Evaluation of Antibacterial and Antioxidant Activities of Novel Benzoxazinones and Benzoxathiinones |
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