Vitamin D Deficiency: Defining, Prevalence, Causes, and Strategies of Addressing

There are variable definitions of vitamin D deficiency, based on different thresholds of serum 25-hydroxyvitamin D (25(OH)D); this has a major bearing on the prevalence estimates of vitamin D deficiency and consequently on the magnitude of the public health issue of low vitamin D status. Despite thi...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Calcified tissue international 2020-01, Vol.106 (1), p.14-29
1. Verfasser: Cashman, Kevin D.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 29
container_issue 1
container_start_page 14
container_title Calcified tissue international
container_volume 106
creator Cashman, Kevin D.
description There are variable definitions of vitamin D deficiency, based on different thresholds of serum 25-hydroxyvitamin D (25(OH)D); this has a major bearing on the prevalence estimates of vitamin D deficiency and consequently on the magnitude of the public health issue of low vitamin D status. Despite this, there is widespread acknowledgement of the presence of vitamin D deficiency, even using the most conservative serum 25(OH)D threshold of
doi_str_mv 10.1007/s00223-019-00559-4
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_2221564365</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2221564365</sourcerecordid><originalsourceid>FETCH-LOGICAL-c441t-80c81db0e43b9e590ebebf5dad9f82d3371ac7dd99933d4e89c6dfafb62684893</originalsourceid><addsrcrecordid>eNp9kEtLw0AQxxdRbK1-AQ8S8NrV2Uc2WW-l9QUFCz7wtmyyk5LSpnU3EfrtjU3Vm6cZZv4P-BFyzuCKASTXAYBzQYFpChDHmsoD0mdScAopTw5JH1jCqFbJe4-chLAAYFIpdUx6goHSUoo-mb2VtV2VVTSJJliUeYlVvr3Z7VVZzYfRzOOnXbZXHEZj2wQMw8hWLnquva1xXmKI1kU0cs5jCK3jlBwVdhnwbD8H5PXu9mX8QKdP94_j0ZTmUrKappCnzGWAUmQaYw2YYVbEzjpdpNwJkTCbJ85prYVwElOdK1fYIlNcpTLVYkAuu9yNX380GGqzWDe-aisN55zFSgoVtyreqXK_DsFjYTa-XFm_NQzMN0TTQTQtRLODaGRruthHN9kK3a_lh1orEJ0gtK9qjv6v-5_YL2AVfAA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2221564365</pqid></control><display><type>article</type><title>Vitamin D Deficiency: Defining, Prevalence, Causes, and Strategies of Addressing</title><source>SpringerLink Journals - AutoHoldings</source><creator>Cashman, Kevin D.</creator><creatorcontrib>Cashman, Kevin D.</creatorcontrib><description>There are variable definitions of vitamin D deficiency, based on different thresholds of serum 25-hydroxyvitamin D (25(OH)D); this has a major bearing on the prevalence estimates of vitamin D deficiency and consequently on the magnitude of the public health issue of low vitamin D status. Despite this, there is widespread acknowledgement of the presence of vitamin D deficiency, even using the most conservative serum 25(OH)D threshold of &lt; 25/30 nmol/L, in both low- and high-income country setting and the pressing need to address this deficiency. While ultraviolet B-rich sunlight stimulates synthesis of vitamin D in skin, there are environmental factors and personal characteristics which prevent or impede such dermal synthesis. There are several complexities and concerns in advocating sun exposure as a public health approach for increasing vitamin D status. This places increased emphasis on addressing vitamin D deficiency through dietary means. However, naturally rich sources of vitamin D are few and infrequently consumed, and nutrition surveillance data from various countries have indicated that habitual vitamin D intakes in the population are much lower than the recommendations. There are a number of strategies that can be considered for the control of micronutrient malnutrition, these include (i) increasing the diversity of foods consumed, (ii) food fortification, and (iii) supplementation. The present narrative review will consider these strategies for addressing low dietary vitamin D intake and consequently lowering the risk of vitamin D deficiency.</description><identifier>ISSN: 0171-967X</identifier><identifier>EISSN: 1432-0827</identifier><identifier>DOI: 10.1007/s00223-019-00559-4</identifier><identifier>PMID: 31069443</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>25-Hydroxyvitamin D ; Biochemistry ; Biomedical and Life Sciences ; Cell Biology ; Dietary intake ; Dietary supplements ; Endocrinology ; Environmental factors ; Life Sciences ; Malnutrition ; Nutrient deficiency ; Orthopedics ; Public health ; Review ; Skin ; Vitamin D ; Vitamin deficiency</subject><ispartof>Calcified tissue international, 2020-01, Vol.106 (1), p.14-29</ispartof><rights>Springer Science+Business Media, LLC, part of Springer Nature 2019</rights><rights>Calcified Tissue International is a copyright of Springer, (2019). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c441t-80c81db0e43b9e590ebebf5dad9f82d3371ac7dd99933d4e89c6dfafb62684893</citedby><cites>FETCH-LOGICAL-c441t-80c81db0e43b9e590ebebf5dad9f82d3371ac7dd99933d4e89c6dfafb62684893</cites><orcidid>0000-0002-8185-1039</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00223-019-00559-4$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00223-019-00559-4$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27903,27904,41467,42536,51297</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31069443$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cashman, Kevin D.</creatorcontrib><title>Vitamin D Deficiency: Defining, Prevalence, Causes, and Strategies of Addressing</title><title>Calcified tissue international</title><addtitle>Calcif Tissue Int</addtitle><addtitle>Calcif Tissue Int</addtitle><description>There are variable definitions of vitamin D deficiency, based on different thresholds of serum 25-hydroxyvitamin D (25(OH)D); this has a major bearing on the prevalence estimates of vitamin D deficiency and consequently on the magnitude of the public health issue of low vitamin D status. Despite this, there is widespread acknowledgement of the presence of vitamin D deficiency, even using the most conservative serum 25(OH)D threshold of &lt; 25/30 nmol/L, in both low- and high-income country setting and the pressing need to address this deficiency. While ultraviolet B-rich sunlight stimulates synthesis of vitamin D in skin, there are environmental factors and personal characteristics which prevent or impede such dermal synthesis. There are several complexities and concerns in advocating sun exposure as a public health approach for increasing vitamin D status. This places increased emphasis on addressing vitamin D deficiency through dietary means. However, naturally rich sources of vitamin D are few and infrequently consumed, and nutrition surveillance data from various countries have indicated that habitual vitamin D intakes in the population are much lower than the recommendations. There are a number of strategies that can be considered for the control of micronutrient malnutrition, these include (i) increasing the diversity of foods consumed, (ii) food fortification, and (iii) supplementation. The present narrative review will consider these strategies for addressing low dietary vitamin D intake and consequently lowering the risk of vitamin D deficiency.</description><subject>25-Hydroxyvitamin D</subject><subject>Biochemistry</subject><subject>Biomedical and Life Sciences</subject><subject>Cell Biology</subject><subject>Dietary intake</subject><subject>Dietary supplements</subject><subject>Endocrinology</subject><subject>Environmental factors</subject><subject>Life Sciences</subject><subject>Malnutrition</subject><subject>Nutrient deficiency</subject><subject>Orthopedics</subject><subject>Public health</subject><subject>Review</subject><subject>Skin</subject><subject>Vitamin D</subject><subject>Vitamin deficiency</subject><issn>0171-967X</issn><issn>1432-0827</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNp9kEtLw0AQxxdRbK1-AQ8S8NrV2Uc2WW-l9QUFCz7wtmyyk5LSpnU3EfrtjU3Vm6cZZv4P-BFyzuCKASTXAYBzQYFpChDHmsoD0mdScAopTw5JH1jCqFbJe4-chLAAYFIpdUx6goHSUoo-mb2VtV2VVTSJJliUeYlVvr3Z7VVZzYfRzOOnXbZXHEZj2wQMw8hWLnquva1xXmKI1kU0cs5jCK3jlBwVdhnwbD8H5PXu9mX8QKdP94_j0ZTmUrKappCnzGWAUmQaYw2YYVbEzjpdpNwJkTCbJ85prYVwElOdK1fYIlNcpTLVYkAuu9yNX380GGqzWDe-aisN55zFSgoVtyreqXK_DsFjYTa-XFm_NQzMN0TTQTQtRLODaGRruthHN9kK3a_lh1orEJ0gtK9qjv6v-5_YL2AVfAA</recordid><startdate>20200101</startdate><enddate>20200101</enddate><creator>Cashman, Kevin D.</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><orcidid>https://orcid.org/0000-0002-8185-1039</orcidid></search><sort><creationdate>20200101</creationdate><title>Vitamin D Deficiency: Defining, Prevalence, Causes, and Strategies of Addressing</title><author>Cashman, Kevin D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c441t-80c81db0e43b9e590ebebf5dad9f82d3371ac7dd99933d4e89c6dfafb62684893</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>25-Hydroxyvitamin D</topic><topic>Biochemistry</topic><topic>Biomedical and Life Sciences</topic><topic>Cell Biology</topic><topic>Dietary intake</topic><topic>Dietary supplements</topic><topic>Endocrinology</topic><topic>Environmental factors</topic><topic>Life Sciences</topic><topic>Malnutrition</topic><topic>Nutrient deficiency</topic><topic>Orthopedics</topic><topic>Public health</topic><topic>Review</topic><topic>Skin</topic><topic>Vitamin D</topic><topic>Vitamin deficiency</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cashman, Kevin D.</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium &amp; Calcified Tissue Abstracts</collection><collection>Nursing &amp; Allied Health Database</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><jtitle>Calcified tissue international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cashman, Kevin D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Vitamin D Deficiency: Defining, Prevalence, Causes, and Strategies of Addressing</atitle><jtitle>Calcified tissue international</jtitle><stitle>Calcif Tissue Int</stitle><addtitle>Calcif Tissue Int</addtitle><date>2020-01-01</date><risdate>2020</risdate><volume>106</volume><issue>1</issue><spage>14</spage><epage>29</epage><pages>14-29</pages><issn>0171-967X</issn><eissn>1432-0827</eissn><abstract>There are variable definitions of vitamin D deficiency, based on different thresholds of serum 25-hydroxyvitamin D (25(OH)D); this has a major bearing on the prevalence estimates of vitamin D deficiency and consequently on the magnitude of the public health issue of low vitamin D status. Despite this, there is widespread acknowledgement of the presence of vitamin D deficiency, even using the most conservative serum 25(OH)D threshold of &lt; 25/30 nmol/L, in both low- and high-income country setting and the pressing need to address this deficiency. While ultraviolet B-rich sunlight stimulates synthesis of vitamin D in skin, there are environmental factors and personal characteristics which prevent or impede such dermal synthesis. There are several complexities and concerns in advocating sun exposure as a public health approach for increasing vitamin D status. This places increased emphasis on addressing vitamin D deficiency through dietary means. However, naturally rich sources of vitamin D are few and infrequently consumed, and nutrition surveillance data from various countries have indicated that habitual vitamin D intakes in the population are much lower than the recommendations. There are a number of strategies that can be considered for the control of micronutrient malnutrition, these include (i) increasing the diversity of foods consumed, (ii) food fortification, and (iii) supplementation. The present narrative review will consider these strategies for addressing low dietary vitamin D intake and consequently lowering the risk of vitamin D deficiency.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>31069443</pmid><doi>10.1007/s00223-019-00559-4</doi><tpages>16</tpages><orcidid>https://orcid.org/0000-0002-8185-1039</orcidid></addata></record>
fulltext fulltext
identifier ISSN: 0171-967X
ispartof Calcified tissue international, 2020-01, Vol.106 (1), p.14-29
issn 0171-967X
1432-0827
language eng
recordid cdi_proquest_journals_2221564365
source SpringerLink Journals - AutoHoldings
subjects 25-Hydroxyvitamin D
Biochemistry
Biomedical and Life Sciences
Cell Biology
Dietary intake
Dietary supplements
Endocrinology
Environmental factors
Life Sciences
Malnutrition
Nutrient deficiency
Orthopedics
Public health
Review
Skin
Vitamin D
Vitamin deficiency
title Vitamin D Deficiency: Defining, Prevalence, Causes, and Strategies of Addressing
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-28T06%3A00%3A48IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Vitamin%20D%20Deficiency:%20Defining,%20Prevalence,%20Causes,%20and%20Strategies%20of%20Addressing&rft.jtitle=Calcified%20tissue%20international&rft.au=Cashman,%20Kevin%20D.&rft.date=2020-01-01&rft.volume=106&rft.issue=1&rft.spage=14&rft.epage=29&rft.pages=14-29&rft.issn=0171-967X&rft.eissn=1432-0827&rft_id=info:doi/10.1007/s00223-019-00559-4&rft_dat=%3Cproquest_cross%3E2221564365%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2221564365&rft_id=info:pmid/31069443&rfr_iscdi=true