Induction of apoptosis in lung carcinoma cells by antiproliferative cyclic lipopeptides from marine algicolous isolate Bacillus atrophaeus strain AKLSR1

[Display omitted] •New surfactin group of cyclic lipopeptides isolated from B atrophaeus AKLSR1.•Isoforms exhibited structural variations in the peptide moiety and lipid chain length.•Cyclic lipopeptides showed good anticancer activity against different cancer cells.•Cyclic lipopeptides inhibited ca...

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Veröffentlicht in:	Process biochemistry (1991) 2019-04, Vol.79, p.142-154
Hauptverfasser:	Routhu, Sunitha Rani, Nagarjuna Chary, R., Shaik, Anver Basha, Prabhakar, S., Ganesh Kumar, C., Kamal, Ahmed
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Anti-cancer Antiproliferatives Apoptosis Bacillus atrophaeus Bioactive compounds Biocompatibility Biomedical materials Biosurfactants Cell cycle Cell death DNA fragmentation Emulsification Endophytes Fatty acids Lipopeptides Lung carcinoma Micelles NMR Nuclear magnetic resonance Organic solvents Structural analysis Surface tension Surfactants Surfactin Toxicity Tumor cell lines Vegetable oils
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