Homing Receptor Expression on Cord Blood T Lymphocytes and the Development of Atopic Eczema in Infants
Expression of the gut-homing receptor integrin αEβ7, but not cutaneous lymphocyte-associated antigen (CLA), on milk allergen-stimulated cord blood T lymphocytes precedes the development of milk-induced eczema in early infancy. The data indicate the involvement of integrin αEβ7 in the development of...
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| Veröffentlicht in: | International archives of allergy and immunology 2001-01, Vol.124 (1-3), p.332-335 |
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| container_issue | 1-3 |
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| container_title | International archives of allergy and immunology |
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| creator | Kohno, Yoichi Shimojo, Naoki Kojima, Hiroyuki Katsuki, Toshiyuki |
| description | Expression of the gut-homing receptor integrin αEβ7, but not cutaneous lymphocyte-associated antigen (CLA), on milk allergen-stimulated cord blood T lymphocytes precedes the development of milk-induced eczema in early infancy. The data indicate the involvement of integrin αEβ7 in the development of infantile allergic eczema and provide a clue to the avoidance of specific allergens and novel therapy targeting homing receptors in food allergy. |
| doi_str_mv | 10.1159/000053749 |
| format | Article |
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| ispartof | International archives of allergy and immunology, 2001-01, Vol.124 (1-3), p.332-335 |
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| source | MEDLINE; Karger Journals Complete; Alma/SFX Local Collection |
| subjects | Allergens - immunology Allergic diseases Antigens, Differentiation, T-Lymphocyte Antigens, Neoplasm Biological and medical sciences Caseins - immunology Cells, Cultured Dermatitis, Atopic - immunology Fetal Blood - immunology Humans Immunopathology Infant Integrins - biosynthesis Lymphocyte Activation Medical sciences Membrane Glycoproteins - biosynthesis Milk Hypersensitivity - immunology Receptors, Lymphocyte Homing - biosynthesis Skin allergic diseases. Stinging insect allergies Skin Diseases T-Lymphocytes - immunology |
| title | Homing Receptor Expression on Cord Blood T Lymphocytes and the Development of Atopic Eczema in Infants |
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