Allergen-Specific Polyclonal Antibodies Reduce Allergic Disease in a Mouse Model of Allergic Asthma

Background: Recombinant allergen-specific immunoglobulin G (IgG) antibody therapy can reduce allergic asthma symptoms by inhibiting the immunoglobulin E (IgE)-mediated allergic response. This study investigated the effect of intranasally administered allergen-specific monoclonal (mAb) and polyclonal...

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Veröffentlicht in:	International Archives of Allergy and Immunology 2006-01, Vol.140 (3), p.261-269
Hauptverfasser:	Moerch, Ulrik, Haahr Hansen, Margit, Vest Hansen, Nils Jakob, Rasmussen, Lone Kjær, Oleksiewicz, Martin B., Frandsen, Torben P., Haurum, John S., Bregenholt, Søren
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Intranasal Allergies Animals Antibodies - administration & dosage Antibodies - immunology Antibodies - therapeutic use Antibody Specificity Asthma Asthma - immunology Asthma - therapy Biological and medical sciences Bronchoalveolar Lavage Fluid - cytology Cell Count Disease Disease Models, Animal Enzyme-Linked Immunosorbent Assay Female Fundamental and applied biological sciences. Psychology Fundamental immunology Histocytochemistry Hypersensitivity, Immediate - immunology Hypersensitivity, Immediate - prevention & control Immunoglobulin E - blood Immunoglobulins Immunopathology Immunotherapy - methods Immunotherapy - standards Lung - immunology Medical sciences Mice Mice, Inbred BALB C Original Paper Ovalbumin - immunology Recombinant Proteins - administration & dosage Recombinant Proteins - therapeutic use Rodents
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