ASSESSMENT OF THE WHEATGRASS EFFECTS ON ANTIOXIDANT CAPACITY AND DNA DAMAGE IN RATS WITH EXPERIMENTAL RENAL FAILURE
In this study, it was aimed to evaluate the effect of wheatgrass on antioxidant capacity and DNA damage in rats with renal failure. In the study, 200-300 g 24 healthy Wistar -Albino male rats obtained from YYU Experimental Animal Unit were used. The rats were randomly divided into 4 groups and each...
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| Veröffentlicht in: | Fresenius environmental bulletin 2019-04, Vol.28 (4), p.2876 |
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| creator | Mis, Leyla Comba, Bahat Basbugan, Yildiray Yasar, Semih Comba, Arzu |
| description | In this study, it was aimed to evaluate the effect of wheatgrass on antioxidant capacity and DNA damage in rats with renal failure. In the study, 200-300 g 24 healthy Wistar -Albino male rats obtained from YYU Experimental Animal Unit were used. The rats were randomly divided into 4 groups and each group was formed with 6 rats. Groups were allocated as; 1. Control Group, 2. Renal Failure Group (Genta Group) 3. Renal Failure + Wheatgrass Group (Genta +Wheatgrass) 4. Wheatgrass Group. Gentamicin sulfate was given intraperitoneal at a dose of 50 mg/kg for 1 week and once a day to the groups with renal failure (Groups 2 and 3). Wheat grass extract (10 ml/kg) was added to the drinking water of the wheatgrass group rats (3rd and 4th groups) once a day. This practice lasted for 4 weeks. Total oxidant, antioxidant quantities, DNA damage were evaluated at the end of 4 weeks. The result that wheatgrass could be useful in renal failure was reached. |
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In the study, 200-300 g 24 healthy Wistar -Albino male rats obtained from YYU Experimental Animal Unit were used. The rats were randomly divided into 4 groups and each group was formed with 6 rats. Groups were allocated as; 1. Control Group, 2. Renal Failure Group (Genta Group) 3. Renal Failure + Wheatgrass Group (Genta +Wheatgrass) 4. Wheatgrass Group. Gentamicin sulfate was given intraperitoneal at a dose of 50 mg/kg for 1 week and once a day to the groups with renal failure (Groups 2 and 3). Wheat grass extract (10 ml/kg) was added to the drinking water of the wheatgrass group rats (3rd and 4th groups) once a day. This practice lasted for 4 weeks. Total oxidant, antioxidant quantities, DNA damage were evaluated at the end of 4 weeks. The result that wheatgrass could be useful in renal failure was reached.</description><identifier>ISSN: 1018-4619</identifier><identifier>EISSN: 1610-2304</identifier><language>eng</language><publisher>Freising: Parlar Scientific Publications</publisher><subject>Antioxidants ; Damage assessment ; Deoxyribonucleic acid ; DNA ; DNA damage ; Drinking water ; Gentamicin ; Kidneys ; Renal failure ; Rodents ; Sulfate ; Wheat</subject><ispartof>Fresenius environmental bulletin, 2019-04, Vol.28 (4), p.2876</ispartof><rights>Copyright Parlar Scientific Publications Apr 2019</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids></links><search><creatorcontrib>Mis, Leyla</creatorcontrib><creatorcontrib>Comba, Bahat</creatorcontrib><creatorcontrib>Basbugan, Yildiray</creatorcontrib><creatorcontrib>Yasar, Semih</creatorcontrib><creatorcontrib>Comba, Arzu</creatorcontrib><title>ASSESSMENT OF THE WHEATGRASS EFFECTS ON ANTIOXIDANT CAPACITY AND DNA DAMAGE IN RATS WITH EXPERIMENTAL RENAL FAILURE</title><title>Fresenius environmental bulletin</title><description>In this study, it was aimed to evaluate the effect of wheatgrass on antioxidant capacity and DNA damage in rats with renal failure. 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The result that wheatgrass could be useful in renal failure was reached.</description><subject>Antioxidants</subject><subject>Damage assessment</subject><subject>Deoxyribonucleic acid</subject><subject>DNA</subject><subject>DNA damage</subject><subject>Drinking water</subject><subject>Gentamicin</subject><subject>Kidneys</subject><subject>Renal failure</subject><subject>Rodents</subject><subject>Sulfate</subject><subject>Wheat</subject><issn>1018-4619</issn><issn>1610-2304</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNotjV9rgzAUxWVssNL1O1zYs5B_JvoYNGrAxqIp7Z6KGvNQxtrV9vsvYzsP93e493LOU7TCHKOYUMSeg0c4jRnH2Wu0WZYzCuJEEE5X0SL7XvX9VhkLbQm2VnColbRVFw6gylLltofWgDRWt0ddBEIudzLX9iMsCyiMhEJuZaVAG-hkeD9oW4M67lSnf4NlA50yYZZSN_tOvUUvfvhc5s0_19G-VDav46atdC6b-IoxvccZouM0JiTxfqSzF2lGeeqc9wPB8zANg3fTxFnChHDMIeEFwWxOxeQ9ybzDdB29_-Veb5fvx7zcT-fL4_YVKk-EYE64wEzQH1SjT0A</recordid><startdate>20190401</startdate><enddate>20190401</enddate><creator>Mis, Leyla</creator><creator>Comba, Bahat</creator><creator>Basbugan, Yildiray</creator><creator>Yasar, Semih</creator><creator>Comba, Arzu</creator><general>Parlar Scientific Publications</general><scope>7ST</scope><scope>7T7</scope><scope>7U7</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>P64</scope><scope>SOI</scope></search><sort><creationdate>20190401</creationdate><title>ASSESSMENT OF THE WHEATGRASS EFFECTS ON ANTIOXIDANT CAPACITY AND DNA DAMAGE IN RATS WITH EXPERIMENTAL RENAL FAILURE</title><author>Mis, Leyla ; Comba, Bahat ; Basbugan, Yildiray ; Yasar, Semih ; Comba, Arzu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p113t-903bcb525ffb3ef789368ddffa21eacaafdcc645477d4d07f7214e87cff29fd13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Antioxidants</topic><topic>Damage assessment</topic><topic>Deoxyribonucleic acid</topic><topic>DNA</topic><topic>DNA damage</topic><topic>Drinking water</topic><topic>Gentamicin</topic><topic>Kidneys</topic><topic>Renal failure</topic><topic>Rodents</topic><topic>Sulfate</topic><topic>Wheat</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mis, Leyla</creatorcontrib><creatorcontrib>Comba, Bahat</creatorcontrib><creatorcontrib>Basbugan, Yildiray</creatorcontrib><creatorcontrib>Yasar, Semih</creatorcontrib><creatorcontrib>Comba, Arzu</creatorcontrib><collection>Environment Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Toxicology Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Environment Abstracts</collection><jtitle>Fresenius environmental bulletin</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mis, Leyla</au><au>Comba, Bahat</au><au>Basbugan, Yildiray</au><au>Yasar, Semih</au><au>Comba, Arzu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>ASSESSMENT OF THE WHEATGRASS EFFECTS ON ANTIOXIDANT CAPACITY AND DNA DAMAGE IN RATS WITH EXPERIMENTAL RENAL FAILURE</atitle><jtitle>Fresenius environmental bulletin</jtitle><date>2019-04-01</date><risdate>2019</risdate><volume>28</volume><issue>4</issue><spage>2876</spage><pages>2876-</pages><issn>1018-4619</issn><eissn>1610-2304</eissn><abstract>In this study, it was aimed to evaluate the effect of wheatgrass on antioxidant capacity and DNA damage in rats with renal failure. 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| ispartof | Fresenius environmental bulletin, 2019-04, Vol.28 (4), p.2876 |
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| language | eng |
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| source | EZB-FREE-00999 freely available EZB journals |
| subjects | Antioxidants Damage assessment Deoxyribonucleic acid DNA DNA damage Drinking water Gentamicin Kidneys Renal failure Rodents Sulfate Wheat |
| title | ASSESSMENT OF THE WHEATGRASS EFFECTS ON ANTIOXIDANT CAPACITY AND DNA DAMAGE IN RATS WITH EXPERIMENTAL RENAL FAILURE |
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