Cancer Immunoediting by Innate Lymphoid Cells

The immune system plays a dual role in cancer. It conveys protective immunity but also facilitates malignant progression, either by sculpting tumor immunogenicity or by creating a microenvironment that can stimulate tumor outgrowth or aid in a subsequent metastatic cascade. Innate lymphoid cells (IL...

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Veröffentlicht in:	Trends in immunology 2019-05, Vol.40 (5), p.415-430
Hauptverfasser:	Wagner, Marek, Koyasu, Shigeo
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens Autoimmune diseases Cancer cancer immunoediting Carcinogenesis Carcinogens Cytokines Cytotoxicity Equilibrium Heterogeneity Hypoxia Immune system immunity Immunogenicity Immunotherapy innate lymphoid cells Ligands Lymphoid cells Metastases Metastasis Transcription factors Tumors
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