Solid phase syntheses of peptoid like arylureido compounds and sequencing of isobars without molecular encoding

Arylureido-backbone containing peptoid-like trimers were prepared using the one-bead-one-compound approach. Isobaric molecules were synthesized from isocyanate precursors that contain alkyl halide handles at the ortho and para -positions in the phenyl ring. After chain extension with a primary amine...

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Veröffentlicht in:Organic & biomolecular chemistry 2019-04, Vol.17 (17), p.424-427
Hauptverfasser: Asif, Kanwal, O'Brien, Gregory L, Goodman, Scott M, Suwal, Sujit
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Sprache:eng
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