Screening of highly-specific aptamers and their applications in paper-based microfluidic chips for rapid diagnosis of multiple bacteria

•A novel “systematic evolution of ligands by exponential enrichment” (SELEX) protocol was developed to screen bacterial aptamers.•A new dual-aptamer, paper-based microfluidic chip was developed for fast diagnosis of three common nosocomial bacteria.•The system possesses many advantages such as faste...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Sensors and actuators. B, Chemical Chemical, 2019-04, Vol.284, p.395-402
Hauptverfasser:	Wang, Chih-Hung, Wu, Jiunn-Jong, Lee, Gwo-Bin
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics Bacteria Bacteria diagnosis Binding Biotin Cellulose esters Cellulose nitrate E coli Microfluidics Paper-based Screening SELEX
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!