Overexpression of phosphorylated nuclear factor-kappa B in tonsillar squamous cell carcinoma and high-grade dysplasia is associated with poor prognosis

Intracellular signals along the epidermal growth factor receptor (EGFR)–Akt–nuclear factor-kappa B (NF-κB) pathway have been associated with carcinogenesis in various malignant neoplasms. This investigation was to evaluate the expression of EGFR, phosphorylated(p)-Akt and p-NF-κB and correlate them...

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Veröffentlicht in:Modern pathology 2005-07, Vol.18 (7), p.924-932
Hauptverfasser: Zhang, Ping L, Pellitteri, Phillip K, Law, Amy, Gilroy, Patricia A, Wood, G Craig, Kennedy, Thomas L, Blasick, Thomas M, Lun, Mingyue, Schuerch, Conrad, Brown, Robert E
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Sprache:eng
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