Neoadjuvant Vinorelbine–Capecitabine Versus Docetaxel–Doxorubicin–Cyclophosphamide in Early Nonresponsive Breast Cancer: Phase III Randomized GeparTrio Trial

Background Among breast cancer patients, nonresponse to initial neoadjuvant chemotherapy is associated with unfavorable outcome. We compared the response of nonresponding patients who continued the same treatment with that of patients who switched to a well-tolerated non–cross-resistant regimen. Met...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	JNCI : Journal of the National Cancer Institute 2008-04, Vol.100 (8), p.542-551
Hauptverfasser:	von Minckwitz, Gunter, Kümmel, Sherko, Vogel, Petra, Hanusch, Claus, Eidtmann, Holger, Hilfrich, Jörn, Gerber, Bernd, Huober, Jens, Costa, Serban Dan, Jackisch, Christian, Loibl, Sibylle, Mehta, Keyur, Kaufmann, Manfred
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antibiotics, Antineoplastic - administration & dosage Antimetabolites, Antineoplastic - administration & dosage Antineoplastic agents Antineoplastic Agents, Alkylating - administration & dosage Antineoplastic Agents, Phytogenic - administration & dosage Antineoplastic Combined Chemotherapy Protocols - administration & dosage Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Biomarkers, Tumor - analysis Breast cancer Breast Neoplasms - chemistry Breast Neoplasms - diagnostic imaging Breast Neoplasms - drug therapy Breast Neoplasms - pathology Breast Neoplasms - surgery Capecitabine Carcinoma, Ductal, Breast - drug therapy Carcinoma, Lobular - drug therapy Chemotherapy Chemotherapy, Adjuvant Clinical outcomes Cyclophosphamide - administration & dosage Deoxycytidine - administration & dosage Deoxycytidine - analogs & derivatives Doxorubicin - administration & dosage Drug Administration Schedule Female Fluorouracil - administration & dosage Fluorouracil - analogs & derivatives Germany Humans Mastectomy, Segmental Medical sciences Middle Aged Neoadjuvant Therapy - methods Neoplasm Staging Patient Compliance Pharmacology. Drug treatments Prospective Studies Side effects Taxoids - administration & dosage Toxicity Treatment Outcome Tumors Ultrasonography, Mammary Vinblastine - administration & dosage Vinblastine - analogs & derivatives
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!