Endocrine Responsiveness and Tailoring Adjuvant Therapy for Postmenopausal Lymph Node-Negative Breast Cancer: A Randomized Trial

Background: The role of adjuvant chemotherapy in postmenopausal patients with lymph node-negative breast cancer is controversial. After demonstrating the efficacy of chemotherapy combined with tamoxifen for postmenopausal patients with lymph node-positive disease, the International Breast Cancer Stu...

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Veröffentlicht in:	JNCI : Journal of the National Cancer Institute 2002-07, Vol.94 (14), p.1054-1065
1. Verfasser:	International Breast Cancer Study Group (IBCSG)
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Antineoplastic agents Antineoplastic Agents, Hormonal - therapeutic use Antineoplastic Combined Chemotherapy Protocols - administration & dosage Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Breast Neoplasms - therapy Chemotherapy Chemotherapy, Adjuvant Cyclophosphamide - administration & dosage Endocrine System - drug effects Fluorouracil - administration & dosage Humans Lymphatic Metastasis - prevention & control Medical sciences Methotrexate - administration & dosage Middle Aged Pharmacology. Drug treatments Postmenopause Quality of Life Tamoxifen - therapeutic use Tamoxifen - toxicity Time Factors Treatment Outcome
Online-Zugang:	Volltext
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