Current concepts and challenges to unravel the role of iodothyronine deiodinases in human neoplasias

Thyroid hormones (THs) are essential for the regulation of several metabolic processes and the energy consumption of the organism. Their action is exerted primarily through interaction with nuclear receptors controlling the transcription of thyroid hormone-responsive genes. Proper regulation of TH l...

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Veröffentlicht in:Endocrine-related cancer 2018-12, Vol.25 (12), p.R625-R645
Hauptverfasser: Goemann, Iuri Martin, Marczyk, Vicente Rodrigues, Romitti, Mirian, Wajner, Simone Magagnin, Maia, Ana Luiza
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Sprache:eng
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