OESOPHAGEAL VARICES ASSOCIATED WITH BUSULPHAN-THIOGUANINE COMBINATION THERAPY FOR CHRONIC MYELOID LEUKAEMIA

5 patients receiving continuous busulphan and 6-thioguanine for chronic myeloid leukaemia (CML) were found to have oesophageal varices associated with abnormal liver function tests. 3 of these cases presented with gastrointestinal haemorrhage and 1 patient died. The 2 other cases had varices discove...

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Veröffentlicht in:	The Lancet (British edition) 1987-11, Vol.330 (8567), p.1050-1052
Hauptverfasser:	Key, NigelS, Emerson, PaulineM, Allan, NormanC, Kelly, PeterM.A., Chapman, RogerW.G., Mcgee, JamesO'D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Busulfan Chronic myeloid leukemia Combination therapy Endoscopy Esophagus Hemorrhage Hyperplasia Hypertension Leukemia Liver Patients Thioguanine
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