IMPAIRED CARDIOVASCULAR RESPONSIVENESS IN LIVER DISEASE
Cardiovascular responsiveness to reflex autonomic stimulation was significantly impaired in patients with cirrhosis compared with control subjects. Peripheral vascular responses to exogenous noradrenaline were also impaired in cirrhotic patients, but peripheral vascular responses to infused adrenali...
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Veröffentlicht in: | The Lancet (British edition) 1975-08, Vol.306 (7931), p.382-385 |
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creator | Lunzer, MichaelR Newman, StephenP Bernard, AlbertG Manghani, KishuK Sherlock, SheilaP.V. Ginsburg, Jean |
description | Cardiovascular responsiveness to reflex autonomic stimulation was significantly impaired in patients with cirrhosis compared with control subjects. Peripheral vascular responses to exogenous noradrenaline were also impaired in cirrhotic patients, but peripheral vascular responses to infused adrenaline and to angiotensin II were similar in both groups. Impaired cardiovascular reactivity in patients with chronic liver disease could preidspose them to circulatory failure after hæmorrhage or surgery and should be considered when prescribing drugd which affect autonomic activity. |
doi_str_mv | 10.1016/S0140-6736(75)92896-2 |
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Peripheral vascular responses to exogenous noradrenaline were also impaired in cirrhotic patients, but peripheral vascular responses to infused adrenaline and to angiotensin II were similar in both groups. 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Peripheral vascular responses to exogenous noradrenaline were also impaired in cirrhotic patients, but peripheral vascular responses to infused adrenaline and to angiotensin II were similar in both groups. Impaired cardiovascular reactivity in patients with chronic liver disease could preidspose them to circulatory failure after hæmorrhage or surgery and should be considered when prescribing drugd which affect autonomic activity.</description><subject>Angiotensin</subject><subject>Angiotensin II</subject><subject>Cirrhosis</subject><subject>Epinephrine</subject><subject>Liver</subject><subject>Liver cirrhosis</subject><subject>Liver diseases</subject><subject>Noradrenaline</subject><subject>Norepinephrine</subject><subject>Patients</subject><subject>Surgery</subject><issn>0140-6736</issn><issn>1474-547X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1975</creationdate><recordtype>article</recordtype><recordid>eNqFkMFLwzAYxYMoOKd_glDwoodq0iZNc5LSZRqo22jc8BayNIUOXWeyCf73Zpt49fS9w3vv4_0AuEbwHkGUPUiIMIwzmma3lNyxJGdZnJyAAcIUxwTTt1Mw-LOcgwvvVxBCnEEyAFS8zApR81FUFvVITBeFLOdVUUc1l7PpRIoFn3ApIzGJqqDraCQkLyS_BGetfvf26vcOwXzMX8vnuJo-ibKoYpNQto3zxjBCWKMNbinDTapR3mqiDWQpJQTiBDLdthlZ6gZZmAaJlplNLMzTcFA6BDfH3o3rP3fWb9Wq37l1eKmSkCVhV5oHFzm6jOu9d7ZVG9d9aPetEFR7RurASO0BKErUgZFKQu7xmLNhwldnnfKms2tjm85Zs1VN3_3T8AOfdmgF</recordid><startdate>19750830</startdate><enddate>19750830</enddate><creator>Lunzer, MichaelR</creator><creator>Newman, StephenP</creator><creator>Bernard, AlbertG</creator><creator>Manghani, KishuK</creator><creator>Sherlock, SheilaP.V.</creator><creator>Ginsburg, Jean</creator><general>Elsevier Ltd</general><general>Elsevier Limited</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7QP</scope><scope>7TK</scope><scope>7U7</scope><scope>7U9</scope><scope>ASE</scope><scope>C1K</scope><scope>FPQ</scope><scope>H94</scope><scope>K6X</scope><scope>K9.</scope><scope>KB~</scope><scope>M7N</scope><scope>NAPCQ</scope></search><sort><creationdate>19750830</creationdate><title>IMPAIRED CARDIOVASCULAR RESPONSIVENESS IN LIVER DISEASE</title><author>Lunzer, MichaelR ; Newman, StephenP ; Bernard, AlbertG ; Manghani, KishuK ; Sherlock, SheilaP.V. ; Ginsburg, Jean</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c279t-8dc9559dac4f794d3a18fa5ac09375504209aff65bad1e03ff61b6e2e0836e213</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1975</creationdate><topic>Angiotensin</topic><topic>Angiotensin II</topic><topic>Cirrhosis</topic><topic>Epinephrine</topic><topic>Liver</topic><topic>Liver cirrhosis</topic><topic>Liver diseases</topic><topic>Noradrenaline</topic><topic>Norepinephrine</topic><topic>Patients</topic><topic>Surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lunzer, MichaelR</creatorcontrib><creatorcontrib>Newman, StephenP</creatorcontrib><creatorcontrib>Bernard, AlbertG</creatorcontrib><creatorcontrib>Manghani, KishuK</creatorcontrib><creatorcontrib>Sherlock, SheilaP.V.</creatorcontrib><creatorcontrib>Ginsburg, Jean</creatorcontrib><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>British Nursing Index</collection><collection>Environmental Sciences and Pollution Management</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>British Nursing Index</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Newsstand Professional</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Nursing & Allied Health Premium</collection><jtitle>The Lancet (British edition)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lunzer, MichaelR</au><au>Newman, StephenP</au><au>Bernard, AlbertG</au><au>Manghani, KishuK</au><au>Sherlock, SheilaP.V.</au><au>Ginsburg, Jean</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>IMPAIRED CARDIOVASCULAR RESPONSIVENESS IN LIVER DISEASE</atitle><jtitle>The Lancet (British edition)</jtitle><date>1975-08-30</date><risdate>1975</risdate><volume>306</volume><issue>7931</issue><spage>382</spage><epage>385</epage><pages>382-385</pages><issn>0140-6736</issn><eissn>1474-547X</eissn><abstract>Cardiovascular responsiveness to reflex autonomic stimulation was significantly impaired in patients with cirrhosis compared with control subjects. 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subjects | Angiotensin Angiotensin II Cirrhosis Epinephrine Liver Liver cirrhosis Liver diseases Noradrenaline Norepinephrine Patients Surgery |
title | IMPAIRED CARDIOVASCULAR RESPONSIVENESS IN LIVER DISEASE |
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