$Assessment of Baseline Clinical Predictive Factors of Response to Cetuximab-Irinotecan in Patients with Irinotecan-Refractory Metastatic Colorectal Cancer$

Assessment of Baseline Clinical Predictive Factors of Response to Cetuximab-Irinotecan in Patients with Irinotecan-Refractory Metastatic Colorectal Cancer

Objective: To identify easily available predictive factors of response to cetuximab-irinotecan in patients with irinotecan-refractory metastatic colorectal cancer. Methods: Retrospective analysis of patients treated with cetuximab (400 mg/m 2 in week 1, 250 mg/m 2 in subsequent weeks) plus irinoteca...

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Veröffentlicht in:	Oncology 2007-01, Vol.73 (3-4), p.185-191
Hauptverfasser:	Hebbar, Mohamed, Di Fioré, Frédéric, Conroy, Thierry, Giraud, Claire, Gasnault, Laurent, Fournier, Charles, Péreira, Renata, Bouché, Olivier, Fournier, Peggy, Deligny, Nathalie, Joly, Jean-Paul, Maes, Patricia, Rad, Emilia, Michel, Pierre, Adenis, Antoine
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - drug therapy Adenocarcinoma - secondary Adult Aged Aged, 80 and over Antibodies, Monoclonal - administration & dosage Antibodies, Monoclonal, Humanized Antineoplastic Combined Chemotherapy Protocols - therapeutic use Camptothecin - administration & dosage Camptothecin - analogs & derivatives Cetuximab Chemotherapy Clinical outcomes Clinical Study Colorectal cancer Colorectal Neoplasms - drug therapy Colorectal Neoplasms - pathology Drug Resistance, Neoplasm Female Humans Immunoenzyme Techniques Male Middle Aged Oncology Prognosis Receptor, Epidermal Growth Factor - metabolism Retrospective Studies Salvage Therapy Survival Rate Treatment Outcome
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