Fluoropyrimidines: A Critical Evaluation

After nearly four decades of clinical experience with the fluoropyrimidines, 5-fluorouracil (5-FU) remains an integral part of chemotherapy for colorectal cancer. A range of 5-FU treatment regimens with or without biochemical modulation are currently used and toxicity appears to be schedule dependen...

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Veröffentlicht in:	Oncology 1999-07, Vol.57 (Suppl 1), p.2-8
Hauptverfasser:	Brito, Rogelio A., Medgyesy, Diana, Zukowski, Thomas H., Royce, Melanie E, Ravandi-Kashani, Farhad, Hoff, Paulo M., Pazdur, Richard
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Animals Antimetabolites, Antineoplastic - metabolism Antineoplastic agents Antineoplastic Agents - administration & dosage Antineoplastic Agents - pharmacology Biological and medical sciences Breast Neoplasms - drug therapy Breast Neoplasms - metabolism Capecitabine Chemotherapy Colorectal Neoplasms - drug therapy Colorectal Neoplasms - metabolism Deoxycytidine - administration & dosage Deoxycytidine - analogs & derivatives Deoxycytidine - pharmacology Drug Combinations Fluorouracil - analogs & derivatives Fluorouracil - metabolism Fluorouracil - pharmacology Humans Leucovorin - pharmacology Medical sciences Oxonic Acid - pharmacology Pharmacology. Drug treatments Pyridines - pharmacology Tegafur - pharmacology Uracil - analogs & derivatives Uracil - pharmacology
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