Baicalin reduces ciclosporin bioavailability by inducing intestinal p‐glycoprotein in rats

Objectives To investigate the effects of multiple doses of baicalin (BG) on the pharmacokinetics of ciclosporin (CsA) in rats and the potential mechanisms. Methods Pharmacokinetic parameters of CsA were determined in male rats after administration of CsA (3 mg/kg, i.g. or i.v.) to rats in the presen...

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