Inhibition of Matrix Metalloproteinase on Hepatic Transforming Growth Factor [beta]1 and Caspase-3 Activation in Hemorrhage

OBJECTIVES: Hemorrhage initiates an inflammatory response that induces the systemic release of cytokines and sequestration of polymorphonuclear neutrophils. Sequestered polymorphonuclear neutrophils release proteases, including matrix metalloproteinases (MMPs) that degrade elements of the extracellu...

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Veröffentlicht in:Academic emergency medicine 2005-09, Vol.12 (9), p.797
Hauptverfasser: Maitra, Subir R, Bhaduri, Sikha, M Raafat El-Maghrabi, Shapiro, Marc J
Format: Artikel
Sprache:eng
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