HYPOTHYROIDISM AND XEROSTOMIA AFTER HEAD AND NECK CANCER RADIATION THERAPY: CASE REPORT AND REVIEW OF LITERATURE

[...]the subjective perception of dry mouth (xerostomia) and reduction in salivary flow rate (hyposalivation) are frequent irreversible complications. [...]the TPOAb were negative (< 20 UI/ml). Because the patient underwent external radiotherapy for hypopharynx carcinoma, both subclinical hypothy...

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Veröffentlicht in:International journal of medical dentistry 2019-01, Vol.9 (1), p.51-56
Hauptverfasser: Leuştean, Letiţia, Bahrim, Delia, Teodoriu, Laura, Ungureanu, Maria Christina, Rusu, Mihai, Ursu, Cornelia, Stadoleanu, Carmen
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container_title International journal of medical dentistry
container_volume 9
creator Leuştean, Letiţia
Bahrim, Delia
Teodoriu, Laura
Ungureanu, Maria Christina
Rusu, Mihai
Ursu, Cornelia
Stadoleanu, Carmen
description [...]the subjective perception of dry mouth (xerostomia) and reduction in salivary flow rate (hyposalivation) are frequent irreversible complications. [...]the TPOAb were negative (< 20 UI/ml). Because the patient underwent external radiotherapy for hypopharynx carcinoma, both subclinical hypothyroidism (increased TSH with normal fT4) and the decreased presence of saliva (xerostomia) were related to the oncologic treatment - external beam therapy. Besides the treatment with low-dose thyroxine (50 pg per day), the patient was referred for a complete dental examination and management. 3.RESULTS AND DISCUSSION These two cases are illustrating the effect of HNCRT on the thyroid gland and oral cavity. According to Palmer, Einhorn, and Wikholm (cited by 10), the incidence of established hypothyroidism was 7.3% in patients with carcinoma of larynx and hypopharynx, 10 years after irradiation.
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[...]the TPOAb were negative (&lt; 20 UI/ml). Because the patient underwent external radiotherapy for hypopharynx carcinoma, both subclinical hypothyroidism (increased TSH with normal fT4) and the decreased presence of saliva (xerostomia) were related to the oncologic treatment - external beam therapy. Besides the treatment with low-dose thyroxine (50 pg per day), the patient was referred for a complete dental examination and management. 3.RESULTS AND DISCUSSION These two cases are illustrating the effect of HNCRT on the thyroid gland and oral cavity. 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subjects Cancer therapies
Case reports
Dental caries
Disease
Dosimetry
Family medical history
Head & neck cancer
Hypopharynx
Hypothyroidism
Larynx
Lymphoma
Medical diagnosis
Oral cavity
Pathology
Patients
Quality of life
Radiation therapy
Saliva
Thyroid
Thyroid gland
Thyroid-stimulating hormone
Thyroxine
Ultrasonic imaging
Xerostomia
title HYPOTHYROIDISM AND XEROSTOMIA AFTER HEAD AND NECK CANCER RADIATION THERAPY: CASE REPORT AND REVIEW OF LITERATURE
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