A method to select for mutator DNA polymerase [delta]s in Saccharomyces cerevisiae

Proofreading DNA polymerases share common short peptide motifs that bind Mg^sup 2+^ in the exonuclease active center; however, hydrolysis rates are not the same for all of the enzymes, which indicates that there are functional and likely structural differences outside of the conserved residues. Sinc...

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Veröffentlicht in:	Genome 2006-04, Vol.49 (4), p.403
Hauptverfasser:	Murphy, Kelly, Darmawan, Hariyanto, Schultz, Amy, Fidalgo da Silva, Elizabeth, Reha-Krantz, Linda J
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Deoxyribonucleic acid DNA DNA polymerase Genetics Mutants Mutation Proteins Studies Yeast Yeasts
Online-Zugang:	Volltext
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