DNA sequence and haplotype variation in two candidate genes for dilated cardiomyopathy in the turkey Meleagris gallopavo

Determining variation in genes is fundamental to understanding their function in the disease state. Cardiac troponin T (cTnT) and phospholamban (PLN) genes have been implicated in dilated cardiomyopathy (DCM) in human and model species. To investigate the role of these 2 candidate genes in DCM in th...

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Veröffentlicht in:	Genome 2007-05, Vol.50 (5), p.463-469
Hauptverfasser:	Lin, K.C, Xu, J, Kamara, D, Geng, T, Gyenai, K, Reed, K.M, Smith, E.J
Format:	Artikel
Sprache:	eng
Schlagworte:	Agriculture Animals Base Sequence Calcium-Binding Proteins - genetics cardiac troponin T cardiomyopathie dilatée Cardiomyopathy Cardiomyopathy, Dilated - genetics Chromosome Mapping cTNT gene dilated cardiomyopathy dindon Diseases Frequency distribution Gallus gallus genes Genetic aspects Genetic Linkage Genetic markers Genomics Haplotypes Heart diseases Meleagris gallopavo Mortality Nucleotide sequence nucleotide sequences phospholamban phospholambane PLN gene Polymorphism, Restriction Fragment Length Polymorphism, Single Nucleotide polymorphisme mononucléotidique poultry diseases Properties restriction fragment length polymorphism Sample size single nucleotide polymorphism Studies Troponin T - genetics troponine cardiaque T troponins turkey turkeys Turkeys - genetics Wild turkeys
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