Support for Allelic Association of a Polymorphic Site in the Promoter Region of the Serotonin Transporter Gene With Risk for Alcohol Dependence

OBJECTIVE: An association between the 5-HTTLPR short variant polymorphism in the promoter region of the serotonin transporter gene and risk for alcohol dependence has been reported from case-control studies that are, however, prone to chance findings related to artifacts of population structure. The...

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Veröffentlicht in:	The American journal of psychiatry 2000-12, Vol.157 (12), p.2045-2047
Hauptverfasser:	Lichtermann, Dirk, Hranilovi, Dubravka, Trixler, Màtyàs, Franke, Petra, Jernej, Branimir, Delmo, Cynthia D., Knapp, Michael, Schwab, Sibylle G., Maier, Wolfgang, Wildenauer, Dieter B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Addictive behaviors Adult Adult and adolescent clinical studies Alcohol-Related Disorders - epidemiology Alcohol-Related Disorders - genetics Alcoholism Alcoholism - epidemiology Alcoholism - genetics Alleles Biological and medical sciences Carrier Proteins - genetics Female Genes Genetic Predisposition to Disease Genetics Hospitalization Humans Male Medical sciences Membrane Glycoproteins - genetics Membrane Transport Proteins Nerve Tissue Proteins Polymorphism, Genetic - genetics Promoter Regions, Genetic - genetics Psychiatry Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Serotonin - genetics Serotonin Plasma Membrane Transport Proteins
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