Polymorphism induced sensitivity to warfarin: A review of the literature

Warfarin is a widely prescribed anticoagulant used for prophylaxis and treatment of venous and arterial thrombosis. Although warfarin is considered very efficacious, it has substantial risks associated with its use, specifically the risk of hemorrhage. Genetic variants associated with the metabolism...

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Veröffentlicht in:	Journal of thrombosis and thrombolysis 2003-06, Vol.15 (3), p.205-212
Hauptverfasser:	PALKIMAS, Michael P, SKINNER, Hillary M, GANDHI, Pritesh J, GARDNER, Alice J
Format:	Artikel
Sprache:	eng
Schlagworte:	Aryl Hydrocarbon Hydroxylases - genetics Aryl Hydrocarbon Hydroxylases - physiology Biological and medical sciences Cytochrome P-450 CYP2C9 Drug toxicity and drugs side effects treatment Genetic Testing - methods Hemorrhage - chemically induced Hemorrhage - etiology Hemorrhage - genetics Humans Medical sciences Pharmacology. Drug treatments Polymorphism, Genetic - physiology Toxicity: blood Warfarin - adverse effects Warfarin - economics Warfarin - metabolism
Online-Zugang:	Volltext
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