Effectiveness and safety of a management protocol to correct over-anticoagulation with oral vitamin K: a retrospective study of 1,043 cases

Background Timely reversal of excessive anticoagulation is important in preventing bleeding complications. The use of vitamin K in correcting over-anticoagulation is widely accepted to be superior to discontinuation of therapy but its effectiveness and safety in large scale cohort studies has not be...

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Veröffentlicht in:	Journal of thrombosis and thrombolysis 2009-04, Vol.27 (3), p.340-347
Hauptverfasser:	Denas, G., Marzot, F., Offelli, P., Stendardo, A., Cucchini, U., Russo, R., Nante, G., Iliceto, S., Pengo, Vittorio
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Anticoagulants - adverse effects Antifibrinolytic Agents - administration & dosage Cardiology Cohort Studies Disease Management Drug Evaluation Drug Overdose Drug Resistance Drug-Related Side Effects and Adverse Reactions Female Hematology Hemorrhage - drug therapy Hemorrhage - prevention & control Humans International Normalized Ratio Male Medicine Medicine & Public Health Middle Aged Retrospective Studies Sex Factors Thromboembolism - chemically induced Vitamin K - administration & dosage Warfarin - adverse effects
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