Anticancer Effect of Marine Sponge-Associated Bacillus pumilus AMK1 Derived Dipeptide Cyclo (-Pro-Tyr) in Human Liver Cancer Cell Line Through Apoptosis and G2/M Phase Arrest

The present study was initiated to identify a novel cytotoxic bioactive molecule from marine sponge Callyspongia fistularis symbionts and to investigate its apoptotic role on human liver cancer cell line (HepG2). The extracts of all the isolated strains (AMK1–AMK12) from sponge Callyspongia fistular...

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Veröffentlicht in:	International journal of peptide research and therapeutics 2020-03, Vol.26 (1), p.445-457
Hauptverfasser:	Karanam, Gayathri, Arumugam, Madan Kumar, Sirpu Natesh, Nagabhishek
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Anatomy Apoptosis Bacillus pumilus Biochemical tests Biochemistry Biomedical and Life Sciences Callyspongia Cell cycle Cytology Cytotoxicity Flow cytometry Hepatocytes Histology Life Sciences Liver Liver cancer Molecular Medicine Morphology Pharmaceutical Sciences/Technology Pharmacology/Toxicology Polymer Sciences rRNA 16S Spectral analysis Symbionts
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