The Tyrosine Kinase Inhibitor Tyrphostin AG 126 Reduces the Development of Colitis in the Rat

Inflammatory bowel disease is characterized by oxidative and nitrosative stress, leukocyte infiltration, up-regulation of the expression of intercellular adhesion molecule-1 (ICAM-1), and up-regulation of P-selectin in the colon. Here we investigate the effects of the tyrosine kinase inhibitor, Tyrp...

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Veröffentlicht in:	Laboratory investigation 2000-09, Vol.80 (9), p.1439-1453
Hauptverfasser:	CUZZOCREA, Salvatore, MCDONALD, Michelle C, MAZZON, Emanuela, MOTA-FILIPE, Helder, LEPORE, Valeria, CICCOLO, Antonio, TERRANOVA, Maria Luisa, BRITTI, Domenico, CAPUTI, Achille P, THIEMERMANN, Christoph
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Digestive system Medical sciences Pharmacology. Drug treatments
Online-Zugang:	Volltext
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