Original article: A randomized trial of aspirin to prevent colorectal adenomas

Background Laboratory and epidemiologic data suggest that aspirin has an antineoplastic effect in the large bowel. Methods We performed a randomized, double-blind trial of aspirin as a chemopreventive agent against colorectal adenomas. We randomly assigned 1121 patients with a recent history of hist...

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Veröffentlicht in:The New England journal of medicine 2003-03, Vol.348 (10), p.891
Hauptverfasser: Baron, John A, Cole, Bernard F, Sandler, Robert S, Haile, Robert W, Ahnen, Dennis, Bresalier, Robert, McKeown-Eyssen, Gail, Summers, Robert W, Rothstein, Richard, Burke, Carol A, Snover, Dale C, Church, Timothy R, Allen, John I, Beach, Michael, Beck, Gerald J, Bond, John H, Byers, Tim, Greenberg, E Robert, Mandel, Jack S, Marcon, Norman, Mott, Leila A, Pearson, Loretta, Saibil, Fred, van Stolk, Rosalind U
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Sprache:eng
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