Rapidly progressive miliary brain metastasis of lung cancer after EGFR tyrosine kinase inhibitor discontinuation: An autopsy report

Miliary brain metastasis is a rare type of brain metastasis, in which carcinoma cells disseminate to numerous foci confined to Virchow–Robin/subpial spaces. Symptoms usually progress within several months, and magnetic resonance imaging (MRI) shows multiple small contrast‐enhancing lesions. We repor...

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Veröffentlicht in:	Neuropathology 2019-04, Vol.39 (2), p.147-155
Hauptverfasser:	Kurihara, Masanori, Koda, Hirotomo, Aono, Hiromi, Sugimoto, Izumi, Sakurai, Yasuhisa, Sano, Terunori, Saito, Yuko, Murayama, Shigeo, Mori, Masaya
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Autopsy Basal ganglia Brain cancer brain neoplasms Cancer Cerebellum Cerebral cortex Chemotherapy Cognitive ability EGFR Enzyme inhibitors Epidermal growth factor Epidermal growth factor receptors Gefitinib Immobilization Lung cancer Lung diseases Magnetic resonance imaging Metastases Metastasis Neuroimaging NMR non‐small‐cell lung carcinoma Nuclear magnetic resonance Protein-tyrosine kinase receptors symptom flare up Thalamus
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